Results 81 to 90 of about 24,902,874 (336)
A basic hypoplastic constitutive model for sand
, 2017 Hypoplastic constitutive models are based on nonlinear tensor functions and are characterized by simple formulation and few parameters. In its early stage, mainly basic hypoplastic constitutive equations were concerned, where the stress tensor is assumed
Wei Wu, Jia-Keng Lin, Xue-tao Wang
semanticscholar +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
A damage-based constitutive model for rock under impacting load
International Journal of Mining Science and Technology, 2014 Using the Splitting Hopkinson Pressure Bar (SHPB) experimental system, investigations were made into the dynamic mechanical performances of underground soft rocks.
Guangming Zhao +2 more
doaj +1 more source
Determination method of constitutive model parameters of dielectric elastomer material
AIP Advances, 2020 The energy conversion process of dielectric elastomers is an electromechanical coupling behavior, and the constitutive model of the material is the basis for studying electromechanical coupling characteristics.
Shi-Ju E +7 more
doaj +1 more source
Zero-thickness interface model with chemical degradation by acid attack [PDF]
, 2019 Carbon dioxide (CO2) storage in abandoned oil/gas reservoirs is considered a viable alternative to reduce greenhouse gas emissions to the atmosphere. An important element of the risk associated with long-term CO2 storage is the loss of integrity of the ...
Carol, Ignacio +3 more
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Band gaps in the relaxed linear micromorphic continuum
, 2014 In this note we show that the relaxed linear micromorphic model recently proposed by the authors can be suitably used to describe the presence of band-gaps in metamaterials with microstructures in which strong contrasts of the mechanical properties are ...
Ghiba, I. -D. +4 more
core +4 more sources
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source