Results 51 to 60 of about 38,046 (312)

A bound-constrained formulation for complex solution phase minimization [PDF]

open access: yesGeoscientific Model Development
Prediction of mineral phase assemblages is essential to better understand the dynamics of the solid Earth, such as metamorphic processes, magmatism and the formation of mineral ore deposits.
N. Riel   +10 more
doaj   +1 more source

Hyperspectral target detection based on transform domain adaptive constrained energy minimization

open access: yesInternational Journal of Applied Earth Observations and Geoinformation, 2021
Traditional hyperspectral target detection methods use spectral domain information for target recognition. Although it can effectively retain intrinsic characteristics of substances, targets in homogeneous regions still cannot be effectively recognized ...
Xiaobin Zhao   +5 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Generalized nesterov’s algorithm for constrained minimization problems on closed convex sets

open access: yesTạp chí Khoa học và Công nghệ, 2023
In this paper, we propose a generalized Nesterov algorithm for the constrained optimization problems on a closed convex set. We prove the convergence as well as the convergence rate of the proposed algorithm.
Pham Quy Muoi   +2 more
doaj   +1 more source

Constrained minimization for monotonic reconstruction [PDF]

open access: yes, 1996
The authors present several innovations in a method for monotonic reconstructions. It is based on the application of constrained minimization techniques for the imposition of monotonicity on a reconstruction.
Kothe, D. B., Rider, W. J.
core  

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Existence and Stability of Standing Waves for Nonlinear Fractional Schrödinger Equations with Hartree Type and Power Type Nonlinearities

open access: yesAdvances in Mathematical Physics, 2016
We consider the standing wave solutions for nonlinear fractional Schrödinger equations with focusing Hartree type and power type nonlinearities. We first establish the constrained minimization problem via applying variational method.
Na Zhang, Jie Xin
doaj   +1 more source

Detection of Insect Damage in Green Coffee Beans Using VIS-NIR Hyperspectral Imaging

open access: yesRemote Sensing, 2020
The defective beans of coffee are categorized into black beans, fermented beans, moldy beans, insect damaged beans, parchment beans, and broken beans, and insect damaged beans are the most frequently seen type.
Shih-Yu Chen   +3 more
doaj   +1 more source

PARROT: Prediction of enzyme abundances using protein-constrained metabolic models.

open access: yesPLoS Computational Biology, 2023
Protein allocation determines the activity of cellular pathways and affects growth across all organisms. Therefore, different experimental and machine learning approaches have been developed to quantify and predict protein abundance and how they are ...
Mauricio Alexander de Moura Ferreira   +2 more
doaj   +1 more source

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