Results 61 to 70 of about 38,046 (312)
Algorithms, 2021 Pairwise comparison matrices play a prominent role in multiple-criteria decision-making, particularly in the analytic hierarchy process (AHP). Another form of preference modeling, called an incomplete pairwise comparison matrix, is considered when one or
Hailemariam Abebe Tekile +2 more
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New iterative methods for equilibrium and constrained convex minimization problems
, 2019 The gradient-projection algorithm (GPA) plays an important role in solving constrained convex minimization problems. In this paper, we combine the GPA and averaged mapping approach to propose implicit and explicit composite iterative schemes for finding ...
Maryam Yazdi
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FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
Sign-Constrained Regularized Loss Minimization
CoRR, 2017 In practical analysis, domain knowledge about analysis target has often been accumulated, although, typically, such knowledge has been discarded in the statistical analysis stage, and the statistical tool has been applied as a black box. In this paper, we introduce sign constraints that are a handy and simple representation for non-experts in generic ...
Tsuyoshi Kato +2 more
openaire +2 more sources
, 2015 The authors propose a mathematical model to minimize the project total cost where there are multiple resources constrained by maximum availability. They assume the resources as renewable and the activities can use any subset of resources requiring any ...
Tereso, Anabela Pereira, Moutinho, Rui
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Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
An Augmented Penalization Algorithm for the Equality Constrained Minimization Problem
Trends in Computational and Applied Mathematics, 2002 In this contribution an iterative method for solving the nonlinear minimization problem with equality constraints is presented. The method is based on the sequential minimization of the differentiable penalization function known as augmented Lagrangian ...
M.C. MACIEL, G.N. SOTTOSANTO
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Pattern Search Algorithms for Bound Constrained Minimization [PDF]
SIAM Journal on Optimization, 1999 The authors extend pattern search algorithms to bound constrained minimization of the form \[ \begin{aligned}\text{minimize }\quad & f(x)\\ \text{subject to }\quad & 1\leq x\leq u. \end{aligned} \] A general class of feasible point pattern search algorithms is developed and the global convergence to a Karush-Kuhn-Tucker-point is proved.
Robert Michael Lewis, Virginia Torczon
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FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source