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Male infertility is a known risk factor for the development of testicular cancer. In this paper, we analyzed the expression profile of a microRNA panel by real‐time PCR and validated the results by digital PCR. Experimental and bioinformatics analyses allowed us to identify possible biomarkers able to discern men with a higher risk of developing ...
Carmen Ferrara+14 more
wiley +1 more source
Multiculturalism: Construct validity and stability [PDF]
The paper provides an overview of our current knowledge of multiculturalism, which refers to the acceptance of and support for the plural nature of a society among mainstreamers and immigrant groups. Multiculturalism is found to be a multifaceted, unifactorial attitude with a good cross-cultural equivalence.
Saskia R. G. Schalk-Soekar+3 more
openaire +3 more sources
Patient‐derived xenografts (PDXs) can be improved by implantation of a humanized niche. We tested different biomaterials and approaches, and demonstrate that the combination of an injectable biomaterial for scaffold creation plus an intravenous route for acute myeloid leukemia (AML) xenotransplantation provide the most convenient and robust approach to
Daniel Busa+13 more
wiley +1 more source
From test validity to construct validity … and back? [PDF]
Medical Education 2012: 46: 366–371Context Major changes in thinking about validity have occurred during the past century, shifting the focus in thinking from the validity of the test to the validity of test score interpretations. These changes have resulted from the ‘new’ thinking about validity in which construct validity has emerged as the central ...
Melinda Conlee+2 more
openaire +3 more sources
Self-determination theory (SDT) distinguishes types of motivation according to types of self-regulation along a continuum of internalisation. Types of motivation vary in quality and outcomes and are frequently used in research as predictors of ...
B. K. Utvær, G. Haugan
semanticscholar +1 more source
Construct Validity Of The Career Resilience Questionnaire
The construct validity of the Career Resilience Questionnaire (Fourie & VanVuuren, 1998) was investigated by means of an oblique multiple groups factor analysis.The highest factor structure coefficients of several of the items did not coincide with the ...
Gideon P. de Bruin, Charlene C. Lew
doaj +1 more source
Pancreatic ductal adenocarcinoma (PDAC) is a disease with very poor prognosis due to therapeutic limitations. We investigated the antitumor effects of cystatin A (CSTA) in PDAC murine models. We are first to confirm that CSTA enhances T helper type 1‐mediated antitumor effects through promotion of dendritic cells and M1 macrophage activity. CSTA can be
Alessandro Nasti+8 more
wiley +1 more source
The $T_{4}$ and $G_{4}$ constructions of Costas arrays [PDF]
We examine two particular constructions of Costas arrays known as the Taylor variant of the Lempel construction, or the $T_{4}$ construction, and the variant of the Golomb construction, or the $G_{4}$ construction. We connect these constructions with the concept of Fibonacci primitive roots, and show that under the Extended Riemann Hypothesis the $T_{4}
arxiv
Synthesis, construction, and validation of a fractal surface [PDF]
Peer ...
RUELLO, GIUSEPPE+6 more
openaire +3 more sources
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric+11 more
wiley +1 more source