Results 51 to 60 of about 4,856,918 (353)

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Construction of an instrument for evaluating the teaching process in higher education: Content and construct validity

REID (Research and Evaluation in Education)
This study aims to reveal the content validity, construct validity, and reliability of the instrument for evaluating the teaching process in higher education. This research is development research applying the ADDIE model from Molenda.
Risky Setiawan, Wagiran Wagiran, Yasir Alsamiri   +2 more
doaj   +1 more source

Psychometric Properties of a Creativity Scale Developed by Field and Bischoff in Indian Context [PDF]

Human Research in Rehabilitation
A scale developed by Field and Bischoff to measure creativity among students of tertiary education institutions was investigated for its reliability and validity when used to measure creativity among students of tertiary education institutions in India.
Abirami Swaminathan, Maya Rathnasabapathy   +1 more
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

Psychometric properties of the mentor behaviour scale in a sample of Malaysian medical students

Journal of Taibah University Medical Sciences, 2018
Objectives: To determine the psychometric properties of the Mentor Behaviour Scale (MBS), a 15-item inventory that evaluates four supportive mentor behaviours in terms of construct validity and internal consistency.
Jamilah A.M. Mohammad, MEd, Muhamad S.B. Yusoff, PhD   +1 more
doaj   +1 more source

Validity and Reliability of the Persian Version of Sport Perfectionism Scale in Iranian Athletes [PDF]

رشد و یادگیری حرکتی ورزشی, 2013
The aim of this study was to determine the validity and reliability of the Persian version of sport perfectionism scale of Dun et al. (2006). To determine the construct validity of the questionnaire, 393 (230 male and 163 female) athletes with different ...
Ahmad Farrokhi, Ebrahim Motesharee, Rasool Zeyd Abadi, Samira Aghasi, Gholam Reza Parsa   +4 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

Construct Validity Of The Career Resilience Questionnaire

SA Journal of Industrial Psychology, 2002
The construct validity of the Career Resilience Questionnaire (Fourie & VanVuuren, 1998) was investigated by means of an oblique multiple groups factor analysis.The highest factor structure coefficients of several of the items did not coincide with the ...
Gideon P. de Bruin, Charlene C. Lew
doaj   +1 more source

Construct Validity in Scientific Representation: A Philosophical Tour

Nordisk tidsskrift for pedagogikk og kritikk, 2020
This article presents a philosophical tour encircling the concept construct validity. Encapsulated by two major perspectives, realism and antirealism, we visit key topics within the philosophy of educational science such as representation and reference ...
Anders Nordahl-Hansen, Tone Kvernbekk
doaj   +1 more source

Development of a women’s empowerment index for Tanzania from the demographic and health surveys of 2004–05, 2010, and 2015–16

Emerging Themes in Epidemiology, 2021
Background Women’s empowerment is a multidimensional construct which varies by context. These variations make it challenging to have a concrete definition that can be measured quantitatively.
Andrew Evarist Mganga, Jenny Renju, Jim Todd, Michael Johnson Mahande, Seema Vyas   +4 more
doaj   +1 more source