Results 121 to 130 of about 8,837,157 (332)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

SmallTalk: a novel small‐sized fusion tag for peptide expression and purification

open access: yesFEBS Open Bio, EarlyView.
The SmallTalk fusion tag allows for the efficient expression and purification of soluble recombinant proteins or peptides in Escherichia coli. Testing with SmallTalk‐GFP confirmed that the proteins were soluble and folded correctly, while SmallTalk‐Bin1b maintained its antimicrobial activity against various bacterial isolates. This streamlined workflow
Atika Tariq   +3 more
wiley   +1 more source

Constructive Renormalization Theory

open access: yes, 1999
These notes are the second part of a common course on Renormalization Theory given with Professor P. da Veiga at X Jorge Andre Swieca Summer School, Aguas de Lindoia, Brazil, February 7-12, 1999. I emphasize the rigorous non-perturbative or constructive aspects of the theory.
openaire   +2 more sources

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

open access: yesFEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Locomotion rhythm makes power and speed. [PDF]

open access: yesSci Rep, 2023
Bejan A, Gunes U, Almahmoud H.
europepmc   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

open access: yesFEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima   +4 more
wiley   +1 more source

and Development, from the Individual Researcher to research Empires [PDF]

open access: yes, 2012
This paper is dated: it was written at the time of the celebration of the 20 years of activity of the Évora Geophysics Centre (CGE). It comprises a brief appraisal of the evolution of scientific research in Europe and in the United States of America ...
Reis, A. Heitor
core  

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

open access: yesFEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli   +9 more
wiley   +1 more source

Refroidissement d'un volume fini générant de la chaleur : limites de l'approche constructale

open access: yes, 2010
International audienceLa répartition optimale, à l'aide de la théorie constructale, d'un matériau hautement conducteur à l'intérieur d'un volume fini générant de la chaleur est un véritable paradigme. Pourtant, il est difficile de comparer les structures
Bougeard, Daniel   +4 more
core   +1 more source

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