Results 161 to 170 of about 5,380,639 (293)
FEBS Open Bio, EarlyView.The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
Constructal design of I and T-shaped channels used in a resin infusion process
, 2015 The resin infusion is a manufacturing technology usually applied to produce structures made of composite materials widely employed in automotive, marine and aerospace industries.
dos Santos, Elizaldo Domingues +7 more
core
Effect of Reverting Channels on Heat Transfer Performance of Microchannels with Different Geometries
Journal of Applied Fluid Mechanics, 2017 This study investigated the effect of reverting microchannels inside a heat sink on increase of cooling rate as well as the effect of their different configurations on maximum temperature and pressure drop. Based on the convection heat transfer mechanism,
Mahsa Farzaneh +2 more
doaj
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
FEBS Open Bio, EarlyView.BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
On the theory and construction of k-clusters [PDF]
The Computer Journal, 1972 openaire +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
, 2016 碩士本研究依據Adrian Bejan所著作的Design with Constructal Theory，改變太陽花散熱鰭片結構外型，探討不同結構外型的散熱鰭片對於熱傳特性的影響。維持太陽花散熱鰭片的總表面積，改變其苗條度、鰭片的分叉數量、無因次化參數D ̃以及無因次化參數R ̃，並且運用數值模擬分析改變鰭片結構對於熱阻的變化。散熱鰭片使用的材料為鋁；發熱源使用的材料為銅，熱源給予固定瓦數加熱。給定固定風速使用強制對流的方式散熱。考慮K-epsilon紊流模型以及能量方程式，數值求解方法中壓力 ...
陳煒杰;Chen, Wei-Chieh
core
Constructal theory of aerodynamic design in NACA airfoils for search and rescue UAVs using integrated CFD and ANN approaches. [PDF]
Sci RepShbailat SJ, Ridha HD.
europepmc +1 more source
Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1
FEBS Open Bio, EarlyView.The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source