Results 121 to 130 of about 4,674,321 (263)
Practical Action Nepal annual report 2006-7 [PDF]
Practical Action ITDG Nepal Annual Highlights for 2006-
Practical Action South Asia
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This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Action News issue: summer 1990 [PDF]
The summer 1990 issue of Action News, which was a community newsletter issued by the Washington County Community Action ...
Washington County Community Action Organization (Or.)
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This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Reflecting on the arts in social action: possibilities for creative engagement in action learning
Using my own experience in integrating the arts and Action Learning, I discuss creative expression as a principal strategy in fostering social change and in advancing social betterment.
Moxley, David
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Action News issue: spring 1989 [PDF]
The spring 1989 issue of Action News, which was a community newsletter issued by the Washington County Community Action ...
Washington County Community Action Organization (Or.)
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High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Action News issue: winter 1992 [PDF]
The winter 1992 issue of Action News, which was a community newsletter issued by the Washington County Community Action ...
Washington County Community Action Organization (Or.)
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Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source

