Results 101 to 110 of about 2,187,228 (292)

Five-dimensional N = 4 Supersymmetric Mechanics

Acta Polytechnica, 2011
We perform an su(2) Hamiltonian reduction in the bosonic sector of the su(2)-invariant action for two free (4, 4, 0) supermultiplets. As a result, we get the five dimensional N = 4 supersymmetric mechanics describing the motion of an isospin carrying ...
S. Bellucci, S. Krivonos, A. Sutulin
doaj  

Artificial intelligence application for reflection development through the implementation of the orienting basis of reflective action for students of the pedagogical departments

Russian Journal of Education and Psychology
This article considers the actual issue about reflection development because despite various reflection development practice existence there are no precise tools for reflective action formation.
Sofya I. Dreytser
doaj   +1 more source

New classes of modified teleparallel gravity models

Physics Letters B, 2017
New classes of modified teleparallel theories of gravity are introduced. The action of this theory is constructed to be a function of the irreducible parts of torsion f(Tax,Tten,Tvec), where Tax,Tten and Tvec are squares of the axial, tensor and vector ...
Sebastian Bahamonde, Christian G. Böhmer, Martin Krššák   +2 more
doaj   +1 more source

McClure-Smith cosimplicial machinery and the cacti operad

, 2014
McClure and Smith constructed a functor that sends a topological multiplicative operad O to an E_2 algebra TotO. They define in fact an operad D_2 (acting on the totalization TotO) weakly equivalent to the little 2-disks operad.
Tsopméné, Paul Arnaud Songhafouo
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Quantum Super-Integrable Systems as Exactly Solvable Models

Symmetry, Integrability and Geometry: Methods and Applications, 2007
We consider some examples of quantum super-integrable systems and the associated nonlinear extensions of Lie algebras. The intimate relationship between super-integrability and exact solvability is illustrated.
Allan P. Fordy
doaj  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Heterotic string field theory with manifest spacetime supersymmetry

Journal of High Energy Physics
Using the hybrid formalism with manifest N = 1 d = 4 spacetime supersymmetry, we construct the quadratic term in the heterotic superstring field theory action.
Nathan Berkovits, Ulisses M. Portugal
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source