Results 91 to 100 of about 407,747 (298)
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
This paper describes a participatory action research project that was delivered on Saturday mornings to vice-principals (VPs) in two Anglophone school districts in the province of New Brunswick, Canada, in 2022 and 2023.
Garner, Andrea +6 more
core +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
A covariantisation of M5-brane action in dual formulation
Journal of High Energy Physics, 2018 We construct a manifestly diffeomorphic M5-brane action in dual formulation coupled to an eleven-dimensional supergravity target space. The covariantisation is carried out by using (generalised) PST technique with 5 auxiliary scalar fields, which are ...
Sheng-Lan Ko, Pichet Vanichchapongjaroen
doaj +1 more source
Ubiquitination of secretory granules promotes their crinophagic degradation in Drosophila
FEBS Letters, EarlyView.Ubiquitination of secretory granules in Drosophila larval salivary glands is a critical molecular trigger for crinophagy, the lysosomal degradation of unreleased, or low‐quality granules. The E3 ubiquitin ligase Cnot4 is recruited to the surface of secretory granules to induce crinophagy.
Tamás Csizmadia +6 more
wiley +1 more source
Socially-Constructed Metrics for Agile Quality: An Action-Research Study
, 2016 : We present a method to develop socially-constructed metrics for ascertaining agile software development quality. Canonical action research (CAR) is our mode of inquiry, conducted in a key European player of healthcare information systems. The result is
Sharon Coyle (12616027) +1 more
core +1 more source
Reflexivity and Narratives in Action Research: A Discursive Approach
Forum: Qualitative Social Research, 2003 The paper offers an analysis of how narratives may be reflexively used at different stages of the research process as a tool to access the interpretative frameworks that actors use to construct their accounts of events and to make sense of their action ...
Monica Colombo
doaj
Climate Action Survey, 2021: Technical Report
, 2022 Griffith University’s Climate Action Beacon conducted the first of five planned Climate Action Surveys in September-October 2021. The survey aimed to discover what Australians think, feel, and do about climate change and related environmental and ...
Bradley, Graham
core
Molecular Oncology, Volume 20, Issue 6, Page 1429-1452, June 2026.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Low-energy effective action in 5D,N=2 supersymmetric gauge theory
Nuclear Physics B, 2019 We construct N=2 supersymmetric low-energy effective action of 5D,N=2 supersymmetric Yang–Mills (SYM) theory in 5D,N=1 harmonic superspace. It is obtained as a hypermultiplet completion of the leading WlnW-term in the N=1 SYM low-energy effective action
I.L. Buchbinder +2 more
doaj +1 more source