Results 61 to 70 of about 407,747 (298)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Constructive Action Semantics for Core ML

open access: yesBRICS Report Series, 2004
Usually, the majority of language constructs found in a programming language can also be found in many other languages, because language design is based on reuse. This should be reflected in the way we give semantics to programming languages. It can be achieved by making a language description consist of a collection of modules, each defining a single ...
Jørgen Iversen, Peter D. Mosses
openaire   +3 more sources

When referents are seen and heard:A comparative study of constructed action in the discourse of LSFB (French Belgian Sign Language) signers and Belgian French speakers [PDF]

open access: yes, 2023
Constructed action is a referential strategy whereby signers and speakers use their bodies and/or voices to depict referents and their actions. Using a corpus-based study, this chapter compares constructed action in LSFB and Belgian French. It shows both
Vandenitte, Sebastien; id_orcid
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Productive Action

open access: yesКультурно-историческая психология, 2019
The key issue of the paper is the question of the means of Existence of human action and, therefore, of the actor himself/herself. The concept of ‘action’ refers to different types of action performance: effective action, play action, learning action and,
Elkonin B.D.
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Cognitive spaces: Expanding participation framework by looking at signed language interpreters’ discourse and conceptual blending

open access: yesTranslation and Interpreting : the International Journal of Translation and Interpreting Research, 2014
We know from previous research (Wadenjso, 1998; Metzger, 1999; Roy, 2000) that interpreters are active participants within the interpreting event. We know that interpreters interact with the participants, and discourse by negotiating turn-taking, and ...
Julie White Armstrong
doaj  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

3D supersymmetric nonlinear multiple D0-brane action and 4D counterpart of multiple M-wave system

open access: yesJournal of High Energy Physics, 2022
Found is the complete nonlinear action of multiple D0-brane system (mD0) in three dimensional type II superspace which is invariant under rigid D = 3 N $$ \mathcal{N} $$ = 2 spacetime supersymmetry and under local worldline supersymmetry generalizing the
Igor Bandos, Unai D. M. Sarraga
doaj   +1 more source

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