Results 101 to 110 of about 8,621,457 (276)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Construction Innovation: The Implementation of Lean Construction towards Sustainable Innovation [PDF]
The prevalent theory of construction has been seen as a hindrance to construction innovation. The concept of lean construction is concerned with the application of lean thinking to the construction industry.
Goulding, Jack Steven +2 more
core
[abstFig src='/00280002/01.jpg' width=""300"" text='A humanoid robot riding an excavator' ]The following article reviews past and current tendencies and derives and describes opportunities for construction robotics and automation. There substantial evidence in the construction industry, that conventional construction methodology has reached its limits.
openaire +1 more source
This paper deals with a well-known problem in the discussion of argument linking, the flexibility that we find with particular verbs, and the constraints governing the integration of verbs with so-called argument structure constructions. We will show that traditional approaches as well as construction grammar need additional machinery to deal with ...
Vogel, Ralf +4 more
openaire +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Thermal Behaviour Assessment of Brick Utilizing Plastic Waste for Enhanced Insulation Properties
Plastic waste, particularly hazardous types such as high-density polyethylene (HDPE) and Polyethylene terephthalate (PTE), is a critical problem in today’s world.
Nuranis Yasira +4 more
doaj
The relevance of the research topic is manifested in the fact that the strengthening of the Russian identity of the residents of Donbass is taking place in the context of an information war with Ukrainian nationalism.
A. V. Baranov, Yu. V. Kostenko
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
HISTORICAL AND ARCHAEOLOGICAL MODELING OF THE ALBAZIN FORT DURING THE SECOND SIEGE. III
In previous works, the authors presented 3D models of artillery bastions, a powder magazine and dugouts. However, for the most complete three-dimensional visualization of the Albaza fortress, it was necessary to develop three–dimensional models of its ...
Lokhov A.Yu. +2 more
doaj +1 more source

