Results 51 to 60 of about 286,896 (265)
Applicability of Bromilow´s Time-cost Model for Residential Projects in Slovakia
Selected Scientific Papers: Journal of Civil Engineering, 2014 The concept of construction time has been mentioned by most researchers as one of the key factors of a successful project. Time-cost model for rapid estimation of construction time appeared in the world some fifty years ago and the most mentioned is ...
Mačková Daniela, Bašková Renáta
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FEBS Open Bio, EarlyView.Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu +5 more
wiley +1 more source
Embodied Energy and Lifecycle Costs: Questioning (Mis)conceptions about Underground Construction
Buildings, 2019 In the construction community, underground construction is perceived as being significantly more costly and more energy-consuming than comparable surface construction.
Michael Robert Doyle +2 more
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FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Probabilistic sensitivity of the cost of earth moving to the variation of operating conditions
Dyna, 2019 The construction comprises a wide spectrum of variables that need to be analyzed to carry out an adequate project planning to generate profit and to comply with the project technical specifications.
Estefanny Zapata-Montenegro +1 more
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FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
The Influence of Vertical Ground Motion on the Design of Common R/C Frames
Applied SciencesIn this article, the response of reinforced concrete frames concurrently subjected to both horizontal and vertical seismic motions is assessed. The article is not limited to the variation in response quantities but aims to identify which specific design ...
Grigorios Manoukas, Vasilios Tsiggelis
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Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
BuildingsGovernment building projects are particularly complex due to their scale and number of end users, which makes construction prices time-consuming and prone to error.
Kongkoon Tochaiwat, Anuwat Budda
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