Results 91 to 100 of about 278,888 (316)
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Planning Resilient Cities: A Methodological Framework for the Integration of Nature-Based Solutions
Applied SciencesClimate change arguably constitutes the most significant environmental challenge of our time, making the enhancement of urban resilience a global priority. Nature-based Solutions (NbS) have emerged as effective instruments to mitigate some of its impacts,
María I. Rodríguez-Rojas +3 more
doaj +1 more source
An experience of introducing last planner into a UK construction project
, 2003 The Last Planner methodology developed by the Lean Construction Institute is a production control tool which has possible benefits for improving planning in the UK construction industry. Its application has been considered in countries outside the UK but
Porter, Geoff, Johansen, Eric
core
Pricing construction work: a marketing viewpoint
, 2007 Recent work on pricing has shown that neoclassical microeconomic theory (NCMT) is preferred to tendering theory and that implied by absorption, or full-cost, pricing of construction work because of its explicit treatment of market conditions, competitor ...
Smyth, Hedley +5 more
core +1 more source
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
A Metaheuristic-Trained Wavelet Neural Network for Predicting of Soil Liquefaction Based on the Standard Penetration Test Results [PDF]
Journal of Soft Computing in Civil EngineeringEarthquake-induced soil liquefaction is one of the natural hazards that can cause irreparable damages to buildings and infrastructure in addition to threatening human lives.
Ali Reza Ghanizadeh, Ahmad Aziminejad
doaj +1 more source
, 2009 This document provides an overview of the differences and similarities in the objectives and implementation frameworks of the training and employment policies applying to public construction projects in Western Australia and Queensland.
core
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Valuation of Construction Projects Based on of Quantity Scale by using Expert System
Journal of Engineering, 2016 The subject of an valuation of quality of construction projects is one of the topics which it becomes necessary of the absence of the quantity standards in measuring the control works and the quality valuation standards in constructional projects. In the
Entisar Kadhim Rasheed, Ass. Prof. Dr.
doaj
Effects of CFRP sheets on the flexural behavior of high-strength concrete beam
Open EngineeringThe aim of this study is to evaluate numerically the effects of carbon fiber-reinforced polymer (CFRP) sheets strengthening on the flexural performance of high-strength concrete (HSC) beam using ABAQUS 3D finite element (FE) modeling software.
Abduljabbar Rawya A. +4 more
doaj +1 more source