Results 101 to 110 of about 1,904,922 (309)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Effects of CFRP sheets on the flexural behavior of high-strength concrete beam

open access: yesOpen Engineering
The aim of this study is to evaluate numerically the effects of carbon fiber-reinforced polymer (CFRP) sheets strengthening on the flexural performance of high-strength concrete (HSC) beam using ABAQUS 3D finite element (FE) modeling software.
Abduljabbar Rawya A.   +4 more
doaj   +1 more source

Toward Standardised Construction Pipeline Data: Conceptual Minimum Dataset Framework

open access: yesBuildings
The construction industry is a cornerstone of New Zealand (NZ)’s economic growth, yet strategic infrastructure planning is constrained by fragmented and inconsistent pipeline data.
Elrasheid Elkhidir   +4 more
doaj   +1 more source

Report of the Section of the Committee for Civil Engineering in the Term 2007–2010 / Sekcja Inzynierii Przedsiewziec Budowlanych W Kadencji 2007 – 2010. Raport

open access: yesArchives of Civil Engineering, 2011
Streszczenie: Artykuł jest raportem charakteryzujacym srodowisko zajmujace sie technologia, organizacja i ekonomika budownictwa - głównie srodowisko akademickie zgrupowanego wokół Sekcji Inzynierii Przedsiewziec Budowlanych KILiW PAN.
Kapliński O
doaj   +1 more source

Construction Innovation: The Implementation of Lean Construction towards Sustainable Innovation [PDF]

open access: yes, 2011
The prevalent theory of construction has been seen as a hindrance to construction innovation. The concept of lean construction is concerned with the application of lean thinking to the construction industry.
Goulding, Jack Steven   +2 more
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Valuation of Construction Projects Based on of Quantity Scale by using Expert System

open access: yesJournal of Engineering, 2016
The subject of an valuation of quality of construction projects is one of the topics which it becomes necessary of the absence of the quantity standards in measuring the control works and the quality valuation standards in constructional projects. In the
Entisar Kadhim Rasheed, Ass. Prof. Dr.
doaj  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

The Impact of the Safeguard Anti-Ballistic Missile System Construction on Northeastern North Dakota [PDF]

open access: yes
Federal defense projects have let to rapid population changes in many communities. These communities often have experienced rapid growth during the construction and installation phase, followed by a population decrease when the project became operational
Coon, Randal C.   +3 more
core   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

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