Results 121 to 130 of about 1,904,922 (309)

PROJECT SCORECARD IN CONSTRUCTION PROJECTS

open access: yes, 2009
This paper describes performance measurement methodology of construction projects from construction company view. Traditional performance indicators (time, cost, quality) are not sufficient for balanced view of project success or fail. They are lagging indicators because they constitute results of project execution and do not show drivers performance ...
Katić, Dragan, Bevanda, Ladislav
openaire   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Project Labor Agreements in New York State: In the Public Interest [PDF]

open access: yes, 2009
It is especially challenging in these tough economic times for officials within New York City’s and New York State’s many entities to decide how best to use public money for construction and renovation projects.
Kotler, Fred B, J.D.
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Leadership in construction partnering projects: Research methodological perspective [PDF]

open access: yes
In recent years there has been a growing interest in the use of partnering in construction. Central to any successful partnering arrangement is the change in cultural and behavioural characteristics towards mutual trust and understanding.
Amaratunga, Dilanthi   +2 more
core  

A conceptual framework for client financed construction and non-traditional approaches for financing construction work [PDF]

open access: yes, 2012
The basic premise of the client-financed-construction philosophy is that those who commission service providers must not only pay for their services for the cost of their labour, materials, plant and equipment but do so in a manner that adds value to all
Abeysekera, Vasantha
core  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Measuring material wastage on construction sites: a case study of local authority highway projects [PDF]

open access: yes, 2010
The construction industry in the UK is vast. It is one of the largest sectors of the economy with an output of over £100 billion, representing approximately 8% of the country’s GDP.
Swinburne, Jonathan   +2 more
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

THE EFFECT OF CURING METHODS ON THE PROPERTIES OF HIGH PERFORMANCE LIGHTWEIGHT CONCRETE IN HOT DRY WEATHER CONDITIONS

open access: yesJournal of Engineering and Sustainable Development, 2017
This study is concerned with the effect of curing methods and early curing on the some properties of high performance lightweight concrete HPLWC that exposed to effects of hot dry weather conditions to improve the performance of concrete structures ...
Hisham Khaled Ahmed   +2 more
doaj  

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