Results 111 to 120 of about 278,888 (316)
A study of project planning on Libyan construction projects
Construction projects are regularly faced by scheduling problems causing the projects to finish beyond their predetermined due date; this is a global phenomenon.
Greenwood, David +2 more
core
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Project learning enablers within fragmented construction projects
Many studies have affirmed a negative influence of fragmentation on learning and knowledge sharing in construction projects. However, the literature overlooked enablers of learning within this context.
Al-Ashwal, Ali M. (R19426)
core
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Method of planning construction projects, taking into account risk factors [PDF]
This paper presents an original method of planning construction projects, taking into account the influence of potential risk factors. The method is called the Method of Construction Risk Assessment (MOCRA).
Dariusz Skorupka
core
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
A constructive real projective plane
The classical theory of plane projective geometry is examined constructively, using both synthetic and analytic methods. The topics include Desargues's Theorem, harmonic conjugates, projectivities, involutions, conics, Pascal's Theorem, poles and polars.
openaire +2 more sources
Evaluation of Incentive/Disincentive Contracting Methods for Highway Construction Projects
Incentive/Disincentive (I/D) provisions are used by state highway agencies as a contract method when early completion is needed for a highway construction project. I/D can provide encouragement for contractors to complete highway construction projects by
Gao, Ruifei
core
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Investigating learning in construction organizations
Learning in construction has received scant attention within extant theories of generic organizational learning. One of the apparently distinct characteristics of construction organization is that its business mainly runs through projects.
Hogg, Keith +3 more
core

