Results 51 to 60 of about 9,030 (293)
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
, 2003 This accessible, yet scholarly, textbook aims to introduce students to the area of social science theory and research that has come to be known as social constructionism.
Burr, Vivien
core +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
Information, 2017 Organic mathematics is an applied mathematics of philosophical atomism. The order of the chemical elements in the table of elements is the source of order for the logical operations of addition and subtraction of atomic numbers.
Jerry L. R. Chandler
doaj +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
A Plea for Non-Naturalism As Constructionism [PDF]
SSRN Electronic Journal, 2017 Contemporary science seems to be caught in a strange predicament. On the one hand, it holds a firm and reasonable commitment to a healthy naturalistic methodology, according to which explanations of natural phenomena should never overstep the limits of the natural itself.
openaire +3 more sources
Varieties of concretisation : an illustrative example [PDF]
, 2006 This paper illustrates, compares and contrasts a variety of different constructions that can be viewed as serving a role in concretisation - the process of developing concrete artefacts to support a learner in understanding abstract concepts.
Harfield, Antony +2 more
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Screening and epitope characterization of Nidogen‐2‐specific nanobodies
FEBS Open Bio, EarlyView.Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen +9 more
wiley +1 more source
Degrammaticalization and constructionalization: two case studies
Language Sciences, 2013 Degrammaticalization has been characterized as a composite change involving gains in morphosyntactic autonomy or phonetic and/or semantic substance. Such a definition is suggestive of a change (or set of changes) which may profitably be explored from a construction grammar perspective.
Trousdale, Graeme, Norde, Muriel
openaire +1 more source
Empirical modelling in support of constructionism : a case study [PDF]
, 2005 Conventional programming paradigms have limitations where support for constructionist learning is concerned. This paper illustrates the merits of an alternative approach to giving support for constructionist learning, based on the principles of Empirical
Harfield, Antony, Beynon, Meurig
core