Results 51 to 60 of about 14,733 (241)
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Social constructionism in vocational psychology and career development
, 2012 This is the fourth book published in the Sense Publishers Career Development Series which began in 2006. The current work addresses the scholarship of social constructionism and its place in disciplinary and professional endeavours of vocational ...
Schultheiss, Donna E., McIlveen, Peter
core +1 more source
Frontiers in EducationThe growing presence of generative artificial intelligence (GenAI) in educational practice raises questions about how learners and educators live with AI and reshapes questions about how learning unfolds across contemporary learning environments ...
Jimin Lee, Nancy Budwig
doaj +1 more source
A constructionist analysis of the current public administration: the role of the myths [PDF]
Polis: Revista de Stiinte Politice, 2018 This article aims, based on a constructionist analysis, to identify if at the public administration level there is a subjective dimension of the realities of the public space.
Dorina ŢICU
doaj
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Artifacts, Visual Modeling and Constructionism: To Look More Closely, to Watch What Happens
Problemos, 2018 [full article, abstract in English; abstract in Lithuanian] Constructionists operationalize a powerful notion they share with constructivists: individual learning is facilitated by building models of specific ideas, concepts, methods, objects ...
James E. Clayson
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Constructionism as a media paradigm [PDF]
CM. Communication and Media, 2018 Research of the nature of mass communication by using different theoretical approaches has gone a long way since its perception as a transmission of symbolic content (whose aim is to create certain effect used for confirming or questioning social order ...
Marković Branko
doaj
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source