Results 81 to 90 of about 14,733 (241)

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Low threshold: how inclusive is Constructionism?

open access: yes, 2014
The paper discusses the degree of inclusiveness of the Constructionist theory when disabilities and special needs are concerned. It shows the impact of both technology and pedagogy used inside the regular curriculum when good inclusive practices are the ...
MORO, MICHELE, T. Urschitz
core  

Konstruktivisme, konstruksionisme en maatskaplike werk

open access: yesKoers : Bulletin for Christian Scholarship, 2000
Constructivism, constructionism and social work In this article the constructivistic framework of reasoning is illustrated with reference to the premises of the structure determinism of Maturana, Kelly's personality constructs theory, and the radical ...
M.J.M. du Plessis, S.B. Ferreira
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

open access: yesFEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata   +3 more
wiley   +1 more source

Social constructionism

open access: yes, 2003
This accessible, yet scholarly, textbook aims to introduce students to the area of social science theory and research that has come to be known as social constructionism.
Burr, Vivien
core   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

open access: yesFEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn   +2 more
wiley   +1 more source

Identification and characterization of a gene conferring stress resistance in Escherichia coli and cyanobacteria

open access: yesFEBS Open Bio, EarlyView.
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada   +7 more
wiley   +1 more source

Společnost jako sociální konstrukce a text

open access: yesTeorie vědy, 2009
Society as Social Construction and Text The moderate interpretation of the Thomas’ Theorem suggests little more than a failure at the assessment of objective situation. Its radical interpretation allows thinking the existence of new social reality.
Miloslav Petrusek
doaj   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio   +8 more
wiley   +1 more source

Social Constructionism and Psychology

open access: yes, 2021
The chapter focuses on social constructionism as a critical voice in psychology. It describes the assumptions underlying the discipline of (mainstream) psychology before going on to demonstrate the key features of social constructionism and how these ...
Burr, Viv
core   +2 more sources

Home - About - Disclaimer - Privacy