Results 191 to 200 of about 45,474 (261)

Single‐cell Transcriptome Profiling Reveals Gene Regulatory Networks and Key Genes in the Root Epidermis and Cortical Cells Associated with Early Nodulation in Glycine Max

open access: yesAdvanced Science, EarlyView.
Single‐cell transcriptomics of soybean roots soon after rhizobial inoculation reveals epidermal and cortical cell‐specific programs and gene‐regulatory networks acting in symbiosis establishment. We identify an ethylene‐driven regulatory circuit involving WRKY6.3/6.4 transcription factors targeting select Nod19 genes that promotes infection‐thread ...
Yongbin Zhuang   +17 more
wiley   +1 more source

What is the role of cultural competence in ethnic minority consumer engagement? An analysis in community healthcare. [PDF]

open access: yesInt J Equity Health, 2019
Harrison R   +6 more
europepmc   +1 more source

Strategy of Triple‐Gradient in Binary Pixels for Flexible Pressure Sensing with High Sensitivity and Wide‐Range Linearity

open access: yesAdvanced Science, EarlyView.
A flexible pressure sensor with triple‐gradient design of conductivity, modulus, and dimension in binary micro‐dome pixels is proposed. Based on precisely‐designed CNT/PDMS matrix, the device exhibits a linear sensitivity of 974.1 kPa−1 across range up to 1.8 MPa (R2 > 0.99), offering an effective strategy for potential applications in healthcare ...
Yifan Liu   +9 more
wiley   +1 more source

TPI1 Loss Triggers a Metabolite‐Driven Mitochondrial Redox Vulnerability via the SARM1–cADPR–Ca2+ Axis

open access: yesAdvanced Science, EarlyView.
Metabolite‐driven redox stress governs cancer cell senescence. TPI1 deficiency elevates DHAP, initiating SARM1‐dependent cADPR‐Ca2+ release. Mitochondrial ROS surge subsequently induces DNA damage and senescence, offering a conserved therapeutic target in multiple cancers.
Chunyu Liu   +15 more
wiley   +1 more source

A High‐Resolution Self‐Powered Angular Displacement Sensor Based on Triboelectric Nanogenerator With Time‐Grating

open access: yesAdvanced Science, EarlyView.
A self‐powered phase‐encoding sensing paradigm enables direct motion‐to‐time information conversion, providing a compact and autonomous strategy for high resolution angular displacement measurement. ABSTRACT In modern manufacturing and engineering, angular displacement sensors are crucial for motion control and feedback systems in Electromechanical ...
Shuxian Wang   +3 more
wiley   +1 more source

A Glucose Metabolism‐Modulatory Nanobiohybrid Vaccine Platform Promotes Anti‐Tumor Immunity by Orchestrating Autophagy‐Dependent Cross‐Presentation and H2S‐Enhanced NLRP3 Inflammasome Signaling

open access: yesAdvanced Science, EarlyView.
A nanobiohybrid vaccine was designed by constructing a hydrogen‐bonded organic framework coencapsulated with glucose oxidase (GOx) and tumor antigens. This nanobiohybrid vaccine executed a GOx‐catalyzed enzyme reaction that disrupted glucose metabolism and induced redox imbalance in dendritic cells, leading to autophagy‐dependent antigen cross ...
Weidong Wang   +5 more
wiley   +1 more source

Oral Delivery Systems for Food‐Derived Bioactive Peptides: Enhancing Stability, Bioavailability, and Health Benefits

open access: yesAdvanced Science, EarlyView.
Advanced delivery systems—including nanoparticles, nanoemulsions, liposomes, and hydrogels—protect food‐derived bioactive peptides from gastrointestinal degradation and bitterness. These systems enable pH‐responsive release, enhance intestinal absorption, and improve therapeutic efficacy against oxidative stress, metabolic disorders, cancer, and ...
Yu Xu   +5 more
wiley   +1 more source

Regulating Droplet Dynamics via Wormlike Micelle Networks: From Splash Suppression to Precise Confined Spreading

open access: yesAdvanced Science, EarlyView.
As displayed in Graphical Abstract image.tif, a molecular‐design strategy precisely tailors high‐speed droplet dynamics through programmed surfactant co‐assembly. The structural transition into an entangled wormlike micelle network completely suppresses stochastic splashing on fibrous substrates.
Shuling Liu   +6 more
wiley   +1 more source

Current Challenges of Transcription Compartmentalization Research

open access: yesAdvanced Science, EarlyView.
Transcription factors, coactivators, and RNA polymerase II assemble into transcription compartments ranging from small, defined complexes to liquid‐like condensates. This review unifies these seemingly competing descriptions along a single continuum and asks what these compartments have been shown to do, and what they have not, revealing that the most ...
Thomas Quail, Sina Wittmann
wiley   +1 more source

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