Results 91 to 100 of about 7,490,098 (406)

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan   +10 more
wiley   +1 more source

Influence of tribology on global energy consumption, costs and emissions

open access: yes, 2017
Calculations of the impact of friction and wear on energy consumption, economic expenditure, and CO2 emissions are presented on a global scale. This impact study covers the four main energy consuming sectors: transportation, manufacturing, power ...
K. Holmberg, A. Erdemir
semanticscholar   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Survey data on household finance and consumption - research summary and policy use [PDF]

open access: yes
The first part of this paper provides a brief survey of the recent literature that employs survey data on household finance and consumption. Given the breadth of the topic, it focuses on issues that are particularly relevant for policy, namely i) wealth ...
The Eurosystem Household Finance and Consumption Network
core  

Gelişmekte olan piyasalarda enerji tüketimi ve büyüme ilişkisinin panel kantil regresyon ile incelenmesi: VISTA ülkeleri örneği [PDF]

open access: yes, 2017
Energy consumption and economic growth relationship is an important topic for global economy. Most of researchers investigated this relationship with different methods on different macro-economic data.
Gökçe, Altan, Uyar, Umut
core   +1 more source

Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?

open access: yesMolecular Oncology, EarlyView.
 
Chen‐xi Li, Zhong‐cheng Gong
wiley   +1 more source

Environmental Impacts of Promoting New Public Transport Systems in Urban Mobility: A Case Study

open access: yesJournal of Sustainable Development of Energy, Water and Environment Systems, 2017
Urban mobility is highly dependent on private vehicles causing pollution, traffic congestion and traffic accidents. The tram has become one of the most relevant public transport modes in those cities which need to reduce the private vehicle dependency ...
Abel Ortego   +2 more
doaj   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Considering a Consumption Tax [PDF]

open access: yes, 2006
A combination of electronic commerce and the Flat Tax could eliminate the IRS as we know ...
Goldberg, Daniel S.
core   +1 more source

Energy Consumption of Lactating Mothers: Current Situation and Problems [PDF]

open access: yes, 2014
Recommendations on the adequacy of nutrient intake indicate that lactating mothers have higher nutritional needs than do pregnant mothers. High nutrient intake is necessary to help mothers recover after childbirth, produce milk, and maintain the quantity
Fikawati, S. (Sandra)   +3 more
core   +2 more sources

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