Results 41 to 50 of about 115,361,426 (290)
Basic Principle and Contact Analysis of Internal Meshing Gear Drive with Curve Configuration
Jixie chuandong, 2022 Based on gear transmission conjugate-curve theory research， taking the internal meshing gear transmission with curve element as the object， general meshing equation of spatial conjugate curves along the designated contact angle position is derived and ...
Dong Liang +4 more
doaj
A study of normal dynamic parameter models of joint interfaces based on fractal theory
Journal of Advanced Mechanical Design, Systems, and Manufacturing, 2015 The dynamic behaviors of the joint interfaces make a great difference in machine tools, especially in high-end numerical control machines. To provide an assessment of the normal dynamic parameters in contact deformation of elastoplastic solid joint ...
Wenwei LIU +4 more
doaj +1 more source
Materials Research, 2022 Wetting of metal droplet on the solid substrate is a fundamental phenomenon which is applicable to the surface chemistry. When an oscillation field is included in the wetting condition, the wetting process shows significant advancing and receding ...
Wendi Li +4 more
doaj +1 more source
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Analysis of an Elasto-Hydrodynamic Seal by Using the Reynolds Equation
Applied Sciences, 2022 This paper reports numerical studies of an Elasto-Hydrodynamic (EHD) seal, which is being developed for supercritical CO2 (sCO2) turbomachinery applications. Current sCO2 turbomachinery suffers from high leakage rates, which is creating a major roadblock
Sevki Cesmeci +5 more
doaj +1 more source
A finite element procedure for the analysis of thermo-mechanical solids in contact [PDF]
Computers & Structures, 2000 Abstract We present a finite element procedure for the analysis of fully coupled thermo-elasto-plastic response of solids including contact conditions. The continuum mechanics formulation for the solid and contact conditions is summarized and effective finite element techniques for solution are given.
Daniel Pantuso +2 more
openaire +1 more source
FEBS Open Bio, EarlyView.The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley +1 more source
Tykhonov well-posedness of fixed point problems in contact mechanics
Fixed Point Theory and Algorithms for Sciences and Engineering, 2022 We consider a fixed point problem S u = u $\mathcal {S}u=u$ where S : C ( R + ; X ) → C ( R + ; X ) ${\mathcal {S}:C(\mathbb{R}_{+};X)\to C(\mathbb{R}_{+};X)}$ is an almost history-dependent operator.
Mircea Sofonea
doaj +1 more source