Results 41 to 50 of about 2,306 (215)

Demodulation of Spatial Carrier Images: Performance Analysis of Several Algorithms Using a Single Image [PDF]

, 2013
http://link.springer.com/article/10.1007%2Fs11340-013-9741-6#Optical full-field techniques have a great importance in modern experimental mechanics.
Esquis, P., Dupré, J.C., VALLE, Valéry, ROTINAT, René, PICART, Pascal, BORNERT, Michel, BADULESCU, Claudiu, DUPRE, Jean Christophe, EQUIS, Sébastien, GREDIAC, Michel, MOLIMARD, Jerome   +10 more
core   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Basic Principle and Contact Analysis of Internal Meshing Gear Drive with Curve Configuration

Jixie chuandong, 2022
Based on gear transmission conjugate-curve theory research， taking the internal meshing gear transmission with curve element as the object， general meshing equation of spatial conjugate curves along the designated contact angle position is derived and ...
Dong Liang, Sheng Meng, Ming Li, Xiangyang Xu, Zeyin He   +4 more
doaj  

Analysis of an Elasto-Hydrodynamic Seal by Using the Reynolds Equation

Applied Sciences, 2022
This paper reports numerical studies of an Elasto-Hydrodynamic (EHD) seal, which is being developed for supercritical CO2 (sCO2) turbomachinery applications. Current sCO2 turbomachinery suffers from high leakage rates, which is creating a major roadblock
Sevki Cesmeci, Karthik Reddy Lyathakula, Mohammad Fuad Hassan, Shuangbiao Liu, Hanping Xu, Jing Tang   +5 more
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Tykhonov well-posedness of fixed point problems in contact mechanics

Fixed Point Theory and Algorithms for Sciences and Engineering, 2022
We consider a fixed point problem S u = u $\mathcal {S}u=u$ where S : C ( R + ; X ) → C ( R + ; X ) ${\mathcal {S}:C(\mathbb{R}_{+};X)\to C(\mathbb{R}_{+};X)}$ is an almost history-dependent operator.
Mircea Sofonea
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Forward and inverse problems in the mechanics of soft filaments [PDF]

Royal Society Open Science, 2018
Soft slender structures are ubiquitous in natural and artificial systems, in active and passive settings and across scales, from polymers and flagella, to snakes and space tethers. In this paper, we demonstrate the use of a simple and practical numerical
M. Gazzola, L. H. Dudte, A. G. McCormick, L. Mahadevan   +3 more
doaj   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source