Results 61 to 70 of about 4,940,955 (286)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Coffee-stain growth dynamics on dry and wet surfaces

open access: yes, 2016
The drying of a drop containing particles often results in the accumulation of the particles at the contact line. In this work, we investigate the drying of an aqueous colloidal drop surrounded by a hydrogel that is also evaporating.
Boulogne, François   +2 more
core   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Analysis of Dynamic Wetting and Dewetting on a Hydrophobic Surface Using Molecular Kinetic Theory

open access: yesTribology Online
The dynamic wetting and dewetting of a water droplet on a hydrophobic solid surface with an equilibrium contact angle of approximately 100° was investigated using molecular kinetic (MK) theory to model the extension–contraction experiment and numerically
Chinatsu Saito   +3 more
doaj   +1 more source

Contact lines for fluid surface adhesion [PDF]

open access: yesPhysical Review E, 2007
When a fluid surface adheres to a substrate, the location of the contact line adjusts in order to minimize the overall energy. This implies boundary conditions which depend on the characteristic surface deformation energies. We develop a general geometrical framework within which these conditions can be derived in a completely systematic way.
Deserno, M., Müller, M., Guven, J.
openaire   +4 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Simulation Study on Arc Temperature of Urban Rail DC Pantograph-Catenary and Arc Ablation of Contact Line

open access: yesMachines
The high temperature generated by the DC pantograph-catenary arc of urban rail systems will aggravate the wear of the pantograph-catenary system. When the ablation intensifies, it will lead to disconnection accidents on the contact line.
Xiaoying Yu   +5 more
doaj   +1 more source

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Electrically modulated dynamic spreading of drops on soft surfaces

open access: yes, 2015
The intricate interaction between the deformability of a substrate and the dynamic spreading of a liquid drop on the same, under the application of an electrical voltage, has remained far from being well understood.
Chakraborty, Suman   +3 more
core   +1 more source

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