Results 31 to 40 of about 79,606 (257)

A 3D study of the contact surface developed by the contact between the tires and the structural pavements

open access: yesExacta, 2009
The basic aim in this work is to present a new technique to analyze the contact surfaces developed by the contact between the tires and the structural pavements by numerical simulations, using 3D finite element formulations with contact mechanics.
Alex Alves Bandeira   +2 more
doaj   +1 more source

On Applications of Semi-Analytical Methods of Contact Mechanics

open access: yesFrontiers in Mechanical Engineering, 2020
This paper is concerned with possible applications of semi-analytical methods of frictional contact mechanics. The semi-analytical solutions, such as the Method of Memory Diagrams, enable the load-displacement relationship for contact of two axisymmetric
Vladislav V. Aleshin   +1 more
doaj   +1 more source

Mechanics Analysis of Rough Surface Based on Shoulder-Shoulder Contact

open access: yesApplied Sciences, 2021
Proper methods and models for mechanical analysis of rough surface can improve the theory of surface contact. When the topography parameters of two rough surfaces are similar, the contact should be considered shoulder-shoulder rather than top-top.
Qiuping Yu, Jianjun Sun, Zhengbo Ji
doaj   +1 more source

Advances in Contact Mechanics

open access: yesLubricants
Advancements in contact mechanics play an important role in the design of modern mechanical and bio-medical systems, enhancing their efficiency, power density, and reliability [...]
Haichao Liu, Haibo Zhang, Xiaoyu Ding
doaj   +1 more source

Mechanisms of Allergic Contact Dermatitis

open access: yes, 2001
Allergenicity depends on several factors determined by the very physicochemical nature of the molecules themselves, i.e., their capacity to penetrate the horny layer, lipophilicity, and chemical reactivity. The sensitizing property of the majority of contact allergens could be predicted from these characteristics (Patlewicz et al., Contact Dermatitis ...
Rustemeyer, Thomas   +3 more
openaire   +3 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

First approach to unilateral transfemoral amputees' contact mechanics

open access: yesDyna, 2017
The stresses in the hip area have great importance because of their relationship to the health of the joint. Finite element models can predict contact between cartilages, however, contact patterns in unilateral transfemoral amputees have not yet been ...
Isabela Mariaka Flórez   +1 more
doaj   +1 more source

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