Results 31 to 40 of about 79,606 (257)
The basic aim in this work is to present a new technique to analyze the contact surfaces developed by the contact between the tires and the structural pavements by numerical simulations, using 3D finite element formulations with contact mechanics.
Alex Alves Bandeira +2 more
doaj +1 more source
On Applications of Semi-Analytical Methods of Contact Mechanics
This paper is concerned with possible applications of semi-analytical methods of frictional contact mechanics. The semi-analytical solutions, such as the Method of Memory Diagrams, enable the load-displacement relationship for contact of two axisymmetric
Vladislav V. Aleshin +1 more
doaj +1 more source
Mechanics Analysis of Rough Surface Based on Shoulder-Shoulder Contact
Proper methods and models for mechanical analysis of rough surface can improve the theory of surface contact. When the topography parameters of two rough surfaces are similar, the contact should be considered shoulder-shoulder rather than top-top.
Qiuping Yu, Jianjun Sun, Zhengbo Ji
doaj +1 more source
Advancements in contact mechanics play an important role in the design of modern mechanical and bio-medical systems, enhancing their efficiency, power density, and reliability [...]
Haichao Liu, Haibo Zhang, Xiaoyu Ding
doaj +1 more source
Mechanisms of Allergic Contact Dermatitis
Allergenicity depends on several factors determined by the very physicochemical nature of the molecules themselves, i.e., their capacity to penetrate the horny layer, lipophilicity, and chemical reactivity. The sensitizing property of the majority of contact allergens could be predicted from these characteristics (Patlewicz et al., Contact Dermatitis ...
Rustemeyer, Thomas +3 more
openaire +3 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
First approach to unilateral transfemoral amputees' contact mechanics
The stresses in the hip area have great importance because of their relationship to the health of the joint. Finite element models can predict contact between cartilages, however, contact patterns in unilateral transfemoral amputees have not yet been ...
Isabela Mariaka Flórez +1 more
doaj +1 more source

