Results 41 to 50 of about 79,606 (257)
Journal of Vocational Health Studies, 2022 Background: Occupational contact dermatitis is an inflammation of the skin caused by materials found in the work environment. Purpose: To determine the factors associated with Complaints of Occupational Contact Dermatitis among Motorcycle Workshop ...
Monica Sofia Maula +3 more
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Journal of the Mechanical Behavior of Materials, 2019 Adhesion between bodies is strongly influenced by surface roughness. In this note, we try to clarify how the statistical properties of the contacting surfaces affect the adhesion under the assumption of long-range adhesive interactions.
Violano Guido +2 more
doaj +1 more source
Tykhonov well-posedness of fixed point problems in contact mechanics
Fixed Point Theory and Algorithms for Sciences and Engineering, 2022 We consider a fixed point problem S u = u $\mathcal {S}u=u$ where S : C ( R + ; X ) → C ( R + ; X ) ${\mathcal {S}:C(\mathbb{R}_{+};X)\to C(\mathbb{R}_{+};X)}$ is an almost history-dependent operator.
Mircea Sofonea
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
IEEE Access, 2019 Loss of meniscal function due to symptomatic meniscal tears or meniscectomy leads to biomechanical instability and articular cartilage degeneration. Synthetic meniscal implants ought to ideally restore normal joint contact mechanics and thus forfending ...
Duraisamy Shriram +3 more
doaj +1 more source
KL Johnson and contact mechanics [PDF]
Proceedings of the Institution of Mechanical Engineers, Part C: Journal of Mechanical Engineering Science, 2016 In 2008, the Journal of Mechanical Engineering Science was approaching its 50 th anniversary and the editorial board arranged some personal contributions from those who had been material in the journal’s success.
Nowell, D, Hills, D, Barber, J
openaire +2 more sources