Results 41 to 50 of about 96,508 (303)
Mechanisms of Allergic Contact Dermatitis
, 2001 Allergenicity depends on several factors determined by the very physicochemical nature of the molecules themselves, i.e., their capacity to penetrate the horny layer, lipophilicity, and chemical reactivity. The sensitizing property of the majority of contact allergens could be predicted from these characteristics (Patlewicz et al., Contact Dermatitis ...
Rustemeyer, Thomas +3 more
openaire +3 more sources
Variational Time Integrators in Computational Solid Mechanics [PDF]
, 2003 This thesis develops the theory and implementation of variational integrators for computational solid mechanics problems, and to some extent, for fluid mechanics problems as well.
Lew, Adrián José
core +1 more source
LubricantsAdvancements in contact mechanics play an important role in the design of modern mechanical and bio-medical systems, enhancing their efficiency, power density, and reliability [...]
Haichao Liu, Haibo Zhang, Xiaoyu Ding
doaj +1 more source
Mechanics Analysis of Rough Surface Based on Shoulder-Shoulder Contact
Applied Sciences, 2021 Proper methods and models for mechanical analysis of rough surface can improve the theory of surface contact. When the topography parameters of two rough surfaces are similar, the contact should be considered shoulder-shoulder rather than top-top.
Qiuping Yu, Jianjun Sun, Zhengbo Ji
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Contact mechanics modelling of articular cartilage and applications [PDF]
, 2006 Osteoarthritis (OA) is a degenerative disease of articular cartilage. The normal cartilage is known to be an excellent bearing material with remarkable lubricating properties and very low frictional co-efficient and wear and generally survives the ...
Pawaskar, Sainath Shrikant
core
, 2012 A deeper understanding of biomechanical behaviour of human hands becomes fundamental for any human hand-operated Q2 activities. The integration of biomechanical knowledge of human hands into product design process starts to play an increasingly important
Chamoret, Dominique +17 more
core +1 more source
Interface roughness effect on friction map under fretting contact conditions [PDF]
, 2010 In many industrial applications where fretting damage is observed in the contact (e.g. rotor/blade, electrical contacts, assembly joint, axe/wheel, clutch) the external loadings or geometry design cannot be changed. Therefore, the surface preparation and
Mathia, T.G. +5 more
core +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source