Results 61 to 70 of about 2,409,835 (286)

Contact mechanics and friction: Role of adhesion

Friction
This paper presents an overview of the role of adhesion in various tribological phenomena. We discuss (1) adhesion and adhesive hysteresis in rough contacts, (2) adhesive contribution to dry friction, (3) properties of adhesive contacts under tangential ...
Valentin L. Popov, Qiang Li, Iakov A. Lyashenko   +2 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Asynchronous variational contact mechanics [PDF]

Computer Methods in Applied Mechanics and Engineering, 2011
An asynchronous, variational method for simulating elastica in complex contact and impact scenarios is developed. Asynchronous Variational Integrators (AVIs) are extended to handle contact forces by associating different time steps to forces instead of to spatial elements.
Vouga, E., Harmon, D., Tamstorf, R., Grinspun, E.   +3 more
openaire   +3 more sources

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Curvilinear virtual elements for contact mechanics [PDF]

, 2020
The virtual element method (VEM) for curved edges with applications to contact mechanics is outlined within this work. VEM allows the use of non-matching meshes at interfaces with the advantage that these can be mapped to a simple node-to-node contact ...
Hudobivnik B., Aldakheel F, Artioli E., Beirao da Veiga L., Aldakheel F., Beirão da Veiga L, Wriggers P., Wriggers P, Hudobivnik B, Artioli E   +9 more
core   +1 more source

To the 60th Anniversary of Professor Alexander Vladimirovich Manzhirov

Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2017
On May, 24, 2017 the 60th jubilee of Prof. A.V. Manzhirov was celebrated at Ishlinsky Institute for Problems in Mechanics of the Russian Academy of Sciences. Prof. A.V.
Yu N Radayev, V P Padchenko
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Measuring Contact Mechanics Deformations Using DIC through a Transparent Medium

, 2017
This paper describes the experimental methodology used to study the contact mechanics of a rigid, rough surface and a compliant, nominally flat surface using digital image correlation (DIC).
S. E. Rohde, Rohde, S. E., W. G. Sawyer, A. I. Bennett, Bennett, A. I., Angelini, T. E., P. G. Ifju, K. L. Harris, T. E. Angelini, Harris, Kathryn L,, Sawyer, W. G., Ifju, P. G.   +11 more
core   +1 more source

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source