Results 71 to 80 of about 96,508 (303)
Asynchronous variational contact mechanics [PDF]
Computer Methods in Applied Mechanics and Engineering, 2011 An asynchronous, variational method for simulating elastica in complex contact and impact scenarios is developed. Asynchronous Variational Integrators (AVIs) are extended to handle contact forces by associating different time steps to forces instead of to spatial elements.
Vouga, E. +3 more
openaire +3 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
, 2007 Geckos and many insects have evolved elastically anisotropic adhesive tissues with hierarchical structures that allow these animals not only to adhere robustly to rough surfaces but also to detach easily upon movement.
高华健 +2 more
core +1 more source
Demodulation of Spatial Carrier Images: Performance Analysis of Several Algorithms Using a Single Image [PDF]
, 2013 http://link.springer.com/article/10.1007%2Fs11340-013-9741-6#Optical full-field techniques have a great importance in modern experimental mechanics.
Esquis, P. +10 more
core +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
To the 60th Anniversary of Professor Alexander Vladimirovich Manzhirov
Vestnik Samarskogo Gosudarstvennogo Tehničeskogo Universiteta. Seriâ: Fiziko-Matematičeskie Nauki, 2017 On May, 24, 2017 the 60th jubilee of Prof. A.V. Manzhirov was celebrated at Ishlinsky Institute for Problems in Mechanics of the Russian Academy of Sciences. Prof. A.V.
Yu N Radayev, V P Padchenko
doaj +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Effects of surface defects on rolling contact fatigue of 60/40 brass [PDF]
, 1999 A study into effects of surface defects on rolling contact fatigue of 60/40 brass under a maximum contact pressure of 600 MPa and a slide–roll ratio of ?1% was undertaken on a twin-disc rolling–sliding test machine.
Beynon, J. H. +2 more
core +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
, 2013 Polymer contact mechanics is an area of contact mechanics focused on the influence of rheological material properties on the contact of polymer ...
Alexander Kovalev +3 more
core +1 more source