Results 81 to 90 of about 96,508 (303)

Experimental study of sand grains behavior at their contacts with force- and displacement-controlled sliding tests

Underground Space, 2017
Discrete element modeling requires the proper quantification of the behavior of grains at their contacts including the normal force – displacement and tangential force – displacement relationships to be used as input for contact modeling purposes.
K. Senetakis, C.S. Sandeep
doaj   +1 more source

A three-dimensional fractal model of the normal contact characteristics of two contacting rough surfaces

AIP Advances, 2021
According to the common characteristics of elastic mechanics and plastic mechanics expressions, a new model of asperity elastic–plastic contact is developed.
Guosheng Lan, Wan Sun, Xueliang Zhang, Yonghui Chen, Wenbing Tan, Xiang Li   +5 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Elastic and Elastoplastic Contact Mechanics of Concentrated Coated Contacts

Lubricants
Machines operate under increasingly harsher contact conditions, causing significant wear and contact fatigue. Sub-surface stresses are responsible for the premature contact fatigue of rolling element bearings, meshing gears, and cam–follower pairs ...
Patricia M. Johns-Rahnejat, Nader Dolatabadi, Homer Rahnejat   +2 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Contact and Fracture Mechanics

, 2018
This book contains two sections: Chapters 1-7 deal with contact mechanics, and Chapters 8-13 deal with fracture mechanics. The different contributions of this book will cover the various advanced topics of research.

core   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Elastic modulus of hyaluronic acid hydrogels by compression testing

Journal of Materials Science: Materials in Medicine
Hyaluronic acid was crosslinked using 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide and N-hydroxysuccinimide to form hydrogels with low elastic modulus.
Rachel Lee, Emily K. Hall, Bassam A. Aljohani, Jake McClements, Marloes Peeters, Mark Geoghegan   +5 more
doaj   +1 more source

Biomechanical Consequences of Lateral Meniscal Posterior Root Avulsions

Orthopaedic Journal of Sports Medicine, 2015
Objectives: Lateral meniscal posterior root avulsions are commonly found with anterior cruciate ligament (ACL) tears. The purpose of this study was to investigate the biomechanical effects of lateral meniscal posterior root avulsions with and without ...
Andrew G. Geeslin MD, David Marc Civitarese B.A., Travis L. Turnbull PhD, Grant Dornan MSc, Fernando Fuso MD, Robert F. LaPrade MD, PhD   +5 more
doaj   +1 more source