Results 111 to 120 of about 1,589,316 (316)
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
, 2009 Carbon-Nanotube (CNT) coated surfaces are investigated to determine theelectrical contact performance under low force conditions. The surfaces under investigationare vertically aligned multi-walled CNTs formed on a Silicon substrate and coated with anAu ...
Yunus, E.M. +2 more
core +1 more source
Contact Models in Robotics: A Comparative Analysis
IEEE Transactions on RoboticsPhysics simulation is ubiquitous in robotics. Whether in model-based approaches (e.g., trajectory optimization), or model-free algorithms (e.g., reinforcement learning), physics simulators are a central component of modern control pipelines in robotics.
Quentin Le Lidec +5 more
openaire +4 more sources
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Molecular Oncology, EarlyView.Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
Secondary transfer effects of intergroup contact via social identity complexity.
, 2014 Secondary transfer effects (STEs) of intergroup contact refer to the generalization of contact effects from a primary encountered outgroup to attitudes towards secondary outgroups (Pettigrew, 2009). Using two large, cross-sectional data sets from Germany
Hewstone, Miles +4 more
core +1 more source
AgricultureThere are approximately 36.7 million hectares of saline alkali land available in China. To enhance the comprehensive utilization value of coastal saline alkali land and boost crop yields in such areas, it is essential to conduct research on optimizing ...
Nan Xu +7 more
doaj +1 more source
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Interracial Public-Police Contact: Relationships with Police Officers’ Racial and Work-Related Attitudes and Behavior [PDF]
, 2010 In a sample of Flemish police officers (N = 172), we examined whether interracial public-police contact is associated with police officers’ racial and workrelated attitudes and self-reported behavior.
Van Hiel, AlainPP078010010201730000-0003-2286-737XF4EA000E-F0ED-11E1-A9DE-61C894A0A6B4 +8 more
core +1 more source
A new model for contact angle hysteresis
Networks & Heterogeneous Media, 2007 We present a model which explains several experimental observations relating contact angle hysteresis with surface roughness. The model is based on the balance between released capillary energy and dissipation associated with motion of the contact line: it describes the stick–slip behavior of drops on a rough surface using ideas similar to those ...
Antonio DeSimone +2 more
openaire +3 more sources
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source