Results 121 to 130 of about 1,589,316 (316)

A people's Entente Cordiale? The role of implicit attitude in the relationship between English-French contact, levels of categorization, and explicit intergroup attitudes [PDF]

, 2006
The Common Ingroup Identity Model (CIIM) holds that four levels of categorization (the interpersonal, intergroup, and particularly, superordinate group, and dual identity levels) mediate the intergroup contact-bias relationship.
Abrams, Dominic, Eller, Anja
core  

Contact-based model for epidemic spreading on temporal networks [PDF]

, 2019
We present a contact-based model to study the spreading of epidemics by means of extending the dynamic message-passing approach to temporal networks. The shift in perspective from node- to edge-centric quantities enables accurate modeling of Markovian ...
Hövel, Philipp, Philipp Hövel, Lentz, Hartmut, Koher, Andreas, Andreas Koher (2585767), Hartmut H. K. Lentz, Lentz, Hartmut H.  K, James P. Gleeson, Gleeson, James P., Andreas Koher, Hartmut H.K. Lentz (12583786), James P. Gleeson (2334922)   +11 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

The 3D nature of a real un-dismantled electrical contact interface

, 2015
A 3D contact analysis and modeling suite of tools are developed and introduced in this work. The "3D Contact Map" of an electrical contact interface is presented demonstrating the 3D nature of the contact.
Swingler, Jonathan, Constantinos Roussos, Jonathan Swingler, Roussos, Constantinos   +3 more
core   +1 more source

Mixing patterns and the spread of close-contact infectious diseases. [PDF]

, 2006
Surprisingly little is known regarding the human mixing patterns relevant to the spread of close-contact infections, such as measles, influenza and meningococcal disease. This study aims to estimate the number of partnerships that individuals make, their
Edmunds, WJ, Kafatos, G, WJ Edmunds, Edmunds WJ, J Wallinga, Wallinga, J, Kafatos G, G Kafatos, Mossong JR, Mossong, JR, Wallinga J, JR Mossong   +11 more
core   +1 more source

3D Model-based Visual Recognition Method of Aviation Electrical Connector′s Contacts [PDF]

Zhengzhou Daxue xuebao. Gongxue ban
The intelligent insertion assistance technology of aviation electrical connectors based on augmented reality or robotic arms relied on precise prior information such as precise contact positions and sorting information.
WANG Yuntao, ZHANG Shang’an, XU Yingpeng, GENG Junhao   +3 more
doaj   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

Oxygen performance of contact lenses: A human eye model

, 1981
Since Smesler and Ozanics1 demonstrated the affinity of the cornea for atmospheric oxygen, contact lens investigators have become increasingly concerned with maximising oxygen availability to the contact lens wearing cornea.
Carney, Leo G., Efron, Nathan
core