Results 21 to 30 of about 4,200,078 (285)

THREE-DIMENSIONAL CONTACT PROBLEM FOR A TRANSVERSELY ISOTROPIC SOLID

Advanced Engineering Research, 2013
The spatial contact problem with an unknown contact domain is investigated for a transversely isotropic elastic half-space the boundary of which is perpendicular to the planes of isotropy.
Dmitry Alexandrovich Pozharskiy, David Borisovich Davtyan   +1 more
doaj   +1 more source

Wetting of Flat Gradient Surfaces

, 2018
Gradient, chemically modified, flat surfaces enable directed transport of droplets. Calculation of apparent contact angles inherent for gradient surfaces is challenging even for atomically flat ones.
Bormashenko, Edward
core   +1 more source

On the dynamic contact problem with two deformable stamps [PDF]

Известия Саратовского университета. Новая серия: Математика. Механика. Информатика
The problem of the time-harmonic behavior of two deformable semi-infinite stamps lying on a deformable base is considered. It is assumed that the stamps converge with parallel ends in such a way that they form a crack, defect, or tectonic fault in the ...
Babeshko, Vladimir A., Uafa, Samir B., Evdokimova, Olga V., Babeshko, Olga M., Telyatnikov, Ilya S., Evdokimov, Vladimir S.   +5 more
doaj   +1 more source

Asymptotic Approach to Solving the Contact Problem for a Rolling Body with a Thin Deformable Rim

Механика машин, механизмов и материалов, 2023
On the basis of an asymptotic approach to solving the elasticity theory boundary value problem for a thin strip rigidly linked to a non-deformable base, the differential equations are derived for determining the normal and shear loads distributed on the ...
Dmitry A. Chernous, Alena V. Kadnianka
doaj   +1 more source

Analysis of elastic and elastoplastic models when interpreting nanoindentation results [PDF]

Известия Саратовского университета. Новая серия: Математика. Механика. Информатика
One of the current and widely used non-destructive testing methods for monitoring and determining the elastic properties of materials is nanoindentation.
Panfilov, Ivan A., Aizikovich, Sergey M., Vasiliev, Andrey S.   +2 more
doaj   +1 more source

Solution of Contact Problem for Supporting Node of Beam Hinged Plate

Наука и техника, 2019
The paper considers a solution of contact problem for hinged supporting node of beam floor slab (coating). The main goal is to determine a stress state of the area where a plate rests on the wall.
S. V. Bosakov, P. D. Skachok
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Nonlinear Tolerancing: Variation Simulation and Assembly Analysis with Regard to Contact Interaction of Parts

Axioms
The variation analysis is a key tool for ensuring the high quality assembly in the process of developing the technology for manufacturing of aircraft parts. One of the main factors in variations is the deviations in the positioning procedure.
Sergey Lupuleac, Margarita Petukhova, Julia Shinder, Maria Titova, Nadezhda Zaitseva, Maria Churilova   +5 more
doaj   +1 more source