Results 81 to 90 of about 2,623,768 (284)

Effect of load, area of contact, and contact stress on the wear mechanisms of a bonded solid lubricant film [PDF]

A pin on disk type of friction and wear apparatus was used to study the effect of load, contact stress and rider area of contact on the friction and wear properties of polyimide bonded graphite fluoride films.
Fusaro, R. L.
core   +1 more source

Strength through diversity: how cancers thrive when clones cooperate

Molecular Oncology, EarlyView.
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken, Maartje Witsen, Emile E. Voest, Krijn K. Dijkstra   +3 more
wiley   +1 more source

Influence of linear profile modification and loading conditions on the dynamic tooth load and stress of high contact ratio gears [PDF]

A computer simulation for the dynamic response of high-contact-ratio spur gear transmissions is presented. High contact ratio gears have the potential to produce lower dynamic tooth loads and minimum root stress but they can be sensitive to tooth profile
Lee, Chinwai, Lin, Hsiang Hsi, Oswald, Fred B., Townsend, Dennis P.   +3 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Analisa Numerik Contact Stress dan Gesekan Capsule Endoscopy di dalam Usus Kecil [PDF]

, 2015
Salah satu alat yang digunakan untuk menganalisa penyakit pada organ dalam adalah capsule endoscopy yang berfungsi sebagai perekam gambar dari saluran pencernaan.
Qomaruddin, Q. (Qomaruddin)
core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Optimal Design of Spur Gears With Increased Contact Ratio

Journal of Mechanical Engineering
The study is devoted to optimal design of gears with profile contact ratio εα ≥ 2. Optimality criteria formulated as follows: the contact stresses in the pitch point must take a minimum value when all constraints are met, first, when the profile contact ...
Ustynenko Oleksandr, Cherelev Stanislav, Ondruška Juraj, Protasov Roman, Yepifanov Vitalii, Bondarenko Oleksiy, Andrienko Sergij   +6 more
doaj   +1 more source

Contact Characteristics of Active Elbow in High-Pressure Manifold

Shiyou jixie, 2022
In order to investigate the raceway pitting corrosion of the active elbow in high-pressure manifold in oil and gas fields,a large-diameter active elbow of Model 130.2 mm-105 MPa(5 1/8 in-15 000 psi)was taken as an example to investigate the influences of
Zhang Guoyou
doaj  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Contact Analysis and Structural Improvement of the Swivel Joints in High Pressure Manifold

Shiyou jixie, 2018
During the operation of the swivel joint in the oilfield, pitting and obvious indentation of the ball bearing at the joint were observed and affected its operation.
Guo Dengming, Wang Sui, Bian Heman
doaj