Results 51 to 60 of about 14,883 (287)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

From Container to Cluster: Chained Escape Attacks in Kubernetes and Orchestration Platforms

open access: yesIEEE Access
Container virtualization offers a lightweight and agile alternative to traditional virtual machines, yet its reliance on a shared host kernel creates a fundamentally weaker isolation boundary. This architectural choice exposes systems to container escape
Jia-Ning Luo   +2 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Optimal Cloud Orchestration Model of Containerized Task Scheduling Strategy Using Integer Linear Programming: Case Studies of IoTcloudServe@TEIN Project

open access: yesEnergies, 2021
As a playground for cloud computing and IoT networking environment, IoTcloudServe@TEIN has been established in the Trans-Eurasia Information Network (TEIN).
Nawat Swatthong, Chaodit Aswakul
doaj   +1 more source

Understand Your Chains: Towards Performance Profile-based Network Service Management

open access: yes, 2017
Allocating resources to virtualized network functions and services to meet service level agreements is a challenging task for NFV management and orchestration systems.
Karl, Holger, Peuster, Manuel
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A Comprehensive Feature Comparison Study of Open-Source Container Orchestration Frameworks

open access: yesApplied Sciences, 2019
(1) Background: Container orchestration frameworks provide support for management ofcomplex distributed applications. Different frameworks have emerged only recently, and they havebeen in constant evolution as new features are being introduced.
Eddy Truyen   +4 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

On-Demand Virtual Research Environments using Microservices

open access: yes, 2019
The computational demands for scientific applications are continuously increasing. The emergence of cloud computing has enabled on-demand resource allocation.
Capuccini, Marco   +7 more
core   +1 more source

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