Results 101 to 110 of about 151,379 (310)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Numerical method to simulate detonative combustion of hydrogen-air mixture in a containment
Engineering Applications of Computational Fluid Mechanics, 2019 During an accident accompanied by core damage in a water-cooled nuclear reactor, a large amount of hydrogen is generated by fuel clad oxidation and released into the reactor containment.
D. Kim, J. Kim
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Containment : an important part of ending polio [PDF]
The world is working to end polio. We help reduce the risk of eradicated polioviruses being released from the places where they are worked with or stored.324427-A21_324427-A-Ezra_CPR_PolioContainment_Update.pdfWhy it Matters -- Why CDC?
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Time-Limited Aging Analysis of the Containment of Nuclear Power Plants without Monitoring Tendons
EnergiesA prestressed concrete containment is the enclosure structure of a nuclear reactor that serves as the last physical barrier of a nuclear power plant (NPP) safety defense system.
Feng Sun, Guopeng Ren
doaj +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Seepage of contaminants from waste containment
, 2006 An alternative approach to assist the environmental engineer in his care for the geo-environment is described in the stochastic continuum modelling of seepage from waste facilities.
Hashim, Roslan, Ismail, Z.
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Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source