In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
ANALYSIS OF THE NODALISATION INFLUENCE ON SIMULATING ATMOSPHERIC STRATIFICATIONS IN THE EXPERIMENT THAI TH13 WITH THE CONTAINMENT CODE SYSTEM COCOSYS [PDF]
, 2009 Joerg Burkhardt +2 more
openalex +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Design of the containment reservoir in the Lonqueador River basin to flooding mitigation in the Francisco Beltrão urban area [PDF]
, 2022 Camila Daiane Cancelier Steinhorst
openalex
The Impact of United Kingdom and Malaysia's Inherent Health Systems on Their COVID‐19 Responses: A Comparison of Containment Strategies [PDF]
, 2021 Shereen Allaham +4 more
openalex +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
International Journal on HomelessnessTo curb the spread of the coronavirus disease of 2019 (COVID-19) in response to the national lockdown, the City of Tshwane, supported by law enforcement agencies, involuntarily rounded up all people experiencing homelessness. The group, comprising around
Newman Tekwa, Jennifer Makhubela
doaj +1 more source
Analysis of Internal Pressure Capacity of Modular Containment Structure for Small Modular Reactor
, 2019 Woo-Ryong Park, Sung-Soon Yhim
openalex +2 more sources
Preliminary results on 400 fps impact tests of two 2-ft diameter containment models for mobile nuclear reactors [PDF]
Impact tests of two 2-foot diameter containment models for mobile nuclear ...
Dallas, T., Puthoff, R. L.
core +1 more source