Results 81 to 90 of about 2,114,915 (360)

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Evaluation of KRAS and NRAS mutations in metastatic colorectal cancer: an 8‐year study of 10 754 patients in Turkey

open access: yesMolecular Oncology, EarlyView.
This nationwide study evaluated KRAS and NRAS mutations in 10 754 Turkish patients with metastatic colorectal cancer. The results revealed a mutation frequency of 51.1%, with 46.6% having KRAS mutations, 4.5% having NRAS mutations, and 48.5% being wild‐type for both.
Gozde Kavgaci   +6 more
wiley   +1 more source

Responses of nitrobenzene removal performance and microbial community by modified biochar supported zerovalent iron in anaerobic soil

open access: yesScientific Reports
Biochar-supported ZVI have received increasing attention for their potential to remove nitrobenzene in groundwater and soil. However, the capacity of this material to enhance the biological reduction of nitrobenzene and alter microbial communities in ...
Lu Hainan   +7 more
doaj   +1 more source

The Effect of Type Ibc Contamination in Cosmological Supernova Samples

open access: yes, 2004
We explore the effect of contamination of intermediate redshift Type Ia supernova samples by Type Ibc supernovae. Simulating observed samples of Ia and mixed Ibc/Ia populations at a range of redshifts for an underlying cosmological concordance model ...
Homeier, N. L.
core   +1 more source

Design of a microwave radiometer for monitoring high voltage insulator contamination level [PDF]

open access: yes, 2015
Microwave radiometry is a novel method for monitoring contamination levels on high voltage insulators. The microwave radiometer described measures energy emitted from the contamination layer and could provide a safe, reliable, contactless monitoring ...
Jiang, Yan   +5 more
core   +1 more source

Contaminations

open access: yes, 2010
Nel testo si cerca di collegare la tradizionale tipologia teatrale del “teatro all’italiana” alle scenografie “non tradizionali”: un tema di ricerca che guarda con interesse alle innovazioni e alle contaminazioni tra l’architettura e le altre discipline.
Annaloro, M, VESCO, Maria Isabella
openaire   +2 more sources

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Effect of single-value response styles on latent factor model convergence and measures of fit [PDF]

open access: yes, 2017
This research examines the effects of single-value response style contamination on measures of model fit and model convergence issues. A simulation study examines the effects resulting from percentage of contamination, number of manifest, number of ...
Harbaugh, A. G., Liu, Min
core  

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

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