Results 81 to 90 of about 2,241,681 (342)
Molecular Oncology, EarlyView.Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece +18 more
wiley +1 more source
Contaminated Aquatic Sediments [PDF]
Water Environment Research, 2007 A review of the literature published in 2014 relating to the assessment, evaluation and remediation of contaminated aquatic sediments is presented. The review is divided into the following sections: policy and guidance, methodology, distribution, fate and transport, bioavailability, bioaccumulation, risk, toxicity and remediation.
openaire +9 more sources
Survivin and Aurora Kinase A control cell fate decisions during mitosis
Molecular Oncology, EarlyView.Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir +2 more
wiley +1 more source
Molecular Oncology, EarlyView.CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir +12 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Groundwater Contamination [PDF]
Science, 1984 J D, Bredehoeft, T M, Usselman
openaire +4 more sources
npj Materials DegradationAtmospheric Plasma Spray (APS) and Vacuum Plasma Spray (VPS) techniques were used to develop Ti/2 vol.% hBN coatings, for extreme space environments and tested aboard the International Space Station as part of the MISSE-17 (Materials International Space ...
Abhijith Kunneparambil Sukumaran +14 more
doaj +1 more source
, 2007 This article explores how Beijing Hip Hop collective Yin Tsang, visual artist Xu Bing and filmmaker Stephen Chow employ different tactics to negotiate between cosmopolitanism and patriotism. All are involved in a translation of a wide range of cultural forms, a translation that involves a betrayal and pollution of culture - be it music, language or ...
openaire +2 more sources
Assessment of degree of risk from sources of microbial contamination in cleanrooms; 1: Airborne [PDF]
, 2015 The degree of risk from microbial contamination of manufactured products by sources of contamination in healthcare cleanrooms has been assessed in a series of three articles.
Eaton, T., Whyte, W.
core
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source