Results 221 to 230 of about 2,301,972 (303)

Best Practices for Medical Information Global Response Documents from phactMI and MILE. [PDF]

Pharmaceut Med
Wnorowski S, Niemoller F, Glaetzer A, Tamburri R, Vine E, Flick F, Patel M, Hermes-DeSantis ER.   +7 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Illustrating Key Components to Co-Creation Through Preventive Care mHealth Messaging with Underserved Communities and Expert Partners. [PDF]

J Med Syst
Stadnick NA, Geremia C, Cain KL, Oswald W, Watson P, Ibarra M, Nguyen M, Altemimi Z, Hammi N, Bautista M, Alrefaee M, Chu TM, Wagner NM, Vijaykumar S, O'Leary ST, Diaz EA, Aldous J, Rabin BA.   +17 more
europepmc   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Combating Dermatologic Misinformation on Social Media via a Training Program for Health Care Professionals: Protocol for a 2-Phase Pilot Mixed Methods Study.

JMIR Res Protoc
Afolabi A, Brown E, Lyu JC, Ling PM, Rustad AM, Davis AE, Hoffman BL, Pugliano-Mauro M.   +7 more
europepmc   +1 more source

Rangatahi Youth-Led Dissemination Campaign for Cocreated Eating and Well-Being Guidelines: Process and Pilot Implementation Evaluation. [PDF]

JMIR Form Res
Christison L, Railton R, Glassey R, Makirere-Haerewa R, Tipene-Leach D, Swinburn B.   +5 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Co-creation of a national burnout secondary prevention programme in Belgium: a pilot project. [PDF]

BMJ Public Health
Lehaen C, Braeckman L, Scius R, Valdiviezo K, Dendoncker C, Kerckhofs K, Lebrun F, Le Roux I, Mennecier D, Vranken S, Hansez I.   +10 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Co-Creating a Digital Learning Platform for Cross-Sectoral Virtual Consultations: An Action Research Study. [PDF]

Scand J Caring Sci
Bagger B, Nielsen MV, Andersen HM, Høgsgaard D, Hägi-Pedersen MB.   +4 more
europepmc   +1 more source