Results 121 to 130 of about 525,022 (337)
We study the optimal design of organizations under the assumption that agents in a contest care about their relative position. A judicious definition of status categories can be used by a principal in order to influence the agents’ performance.
Moldovanu, Benny +2 more
core
I develop a formal model of political campaigns in which candidates choose how to distribute their resources over two different policy issues. I assume that campaigning on an issue has two simultaneous effects, both rooted in social and cognitive psychology: It increases the perceived quality of the advertising candidate in that issue (persuasion) and ...
openaire +2 more sources
Strength through diversity: how cancers thrive when clones cooperate
Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
Contests with investment [PDF]
Perfectly discriminating contests (or all pay auction) are widely used as a model of situations where individuals devote resources to win some prize.
Münster, Johannes
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Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Contests with multi-tasking [PDF]
The standard contest model in which participants compete in a single dimension is well understood and documented. Multi-dimension extensions are possible but are liable to increase the complexity of the contest structure, mitigating one of its main ...
Clark, Derek J., Konrad, Kai A.
core +3 more sources
Owner-Intruder Contests with Information Asymmetry [PDF]
Owner-Intruder Contests with Information Asymmetry Faheem Farooq, Depts. of Biology and Chemistry, Jay Bisen, Manaeil Hasan, and Akhil Patel, with Dr. Jan Rychtar, Dept. of Mathematics and Discrete Mathematics, and Dr. Dewey T. Taylor, Dept.
Bisen, Jay +3 more
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
We study equilibrium in a multistage race in which players compete in a sequence of simultaneous move component contests. Players may win a prize for winning each component contest, as well as a prize for winning the overall race.
Konrad, Kai A., Kovenock, Dan
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