FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Effectiveness of Meaningful Instructional Design in Improving Students' Mathematical Skills
Journal of Philology and Educational SciencesThis study aims to examine the impact of the Meaningful Instructional Design (MID) model on students' mathematical analytical skills, addressing a gap in previous research, which has yet to explore this critical cognitive domain.
Fredi Ganda Putra +4 more
doaj +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Effort To Improve Student Achievement In Learning Through The Development Of Function Composition Method Of Discussion On The Approach To Contextual Teaching And Learning (CTL) In Class XI IPA 1 Salatiga Christian Senior High School 1 [PDF]
, 2011 Learning mathematics in class XI IPA 1 Salatiga Christian Senior High School 1 needs to be improved because teachers are still learning that involves using the lecture method and mechanistic approach.
Dimas Adi Nugroho, Dimas Adi Nugroho +4 more
core
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Contextual influences on visual statistical learning
, 2022 Vickery, Timothy J.Visual statistical learning describes the unintentional extraction of statistical regularities from visual environments across time or space, and is typically studied using novel stimuli (e.g., symbols unfamiliar to participants ...
Rogers, Leeland Loew
core +1 more source
Implementation and Evaluation of an Adaptive Multimedia Presentation System (AMPS) with Contextual Supplemental Support Media [PDF]
, 2010 Requirements have been captured for a multimedia presentation learning system that adapts content through interactive interventions between the student and tutor [5].
David Newell +7 more
core +4 more sources
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
IMPROVING ENGLISH VOCABULARY MASTERY OF THE FIFTH GRADE STUDENTS OF SDN GURAWAN SURAKARTA BY USING CONTEXTUAL TEACHING AND LEARNING (CTL) [PDF]
, 2010 Muhammad Fitriyanto, IMPROVING ENGLISH VOCABULARY MASTERY OF THE FIFTH GRADE STUDENTS OF SDN GURAWAN SURAKARTA BY USING CONTEXTUAL TEACHING AND LEARNING (CTL) ( A Classroom Action Research).
FITRIYANTO, MUHAMMAD
core
The effect of TPACK-based contextual teaching and learning model on student learning outcomes [PDF]
Background/purpose. Social studies learning outcomes for fourth-grade pupils at Al-Hikmah Islamic Elementary School, Simpar Poncokusumo Malang, East Java, Indonesia, remain poor.
Supriyatno, Triyo +4 more
core +1 more source