Results 101 to 110 of about 125,919 (262)

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

FEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Phosphoinositides and inositol phosphates as molecular glues

FEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry, Alexander J. Cutright, Mong Na Claire Loi, Jessica Martin, Joseph W. Gilligan, Jakub N. Kubina, Michael J. Arambula, Susanna Tanada Palmu, Daniella Zhou, Raymond D. Blind   +9 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

On the relationship between generalised continued fractions and G-continued fractions

Journal of Computational and Applied Mathematics, 1990
Generalised continued fractions, or n-fractions, were used by \textit{M. G. de Bruin} [Generalized continued fractions and a multidimensional Padé table, Thesis (Amsterdam, 1974; Zbl 0273.41028)] in the study of simultaneous rational approximation of functions using rational functions with a common denominator.
openaire   +2 more sources

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

On the numerical stability of the branched continued fraction expansion of the ratio $H_4(a,d+1;c,d;\mathbf{z})/H_4(a,d+2;c,d+1;\mathbf{z})$

Математичні Студії
Continued fractions and their generalization, branched continued fractions, are the effective tools used to study special functions. In this aspect, an important problem of continued fractions and branched continued fractions is the study of their ...
M. V. Dmytryshyn, C. Cesarano, O. Kondur, I.-A. Lutsiv   +3 more
doaj   +1 more source

Some identities of G-continued fractions and generalized continued fractions

Journal of Computational and Applied Mathematics, 1994
Generalized continued fractions and \(G\)-continued fractions are two different types of generalizations of continued fractions, the first one due to M. G. de Bruin, the second one introduced by P. Levrie and R. Piessens. Both types are related to higher order linear recurrence relations (whereas the ordinary ones are related to second order relations).
openaire   +2 more sources

Exact Statistics and Continued Fractions [PDF]

, 1996
JUCS - Journal of Universal Computer Science Volume Nr.
openaire   +6 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source