Results 161 to 170 of about 8,697,543 (404)
Toward a Semiotic Framework for Using Technology in Mathematics Education: The Case of Learning 3D Geometry [PDF]
This paper proposes and examines a semiotic framework to inform the use of technology in mathematics education. Semiotics asserts that all cognition is irreducibly triadic, of the nature of a sign, fallible, and thoroughly immersed in a continuing ...
Nason, Rodney, Yeh, Andy
core +1 more source
Long‐Term Evaluation of Givinostat in Duchenne Muscular Dystrophy, and Natural History Comparisons
ABSTRACT Objectives This ongoing, open‐label extension study is evaluating the long‐term safety, tolerability, and efficacy of givinostat, a Class I and II histone deacetylase inhibitor, in patients with Duchenne muscular dystrophy (DMD). Methods The recruited patients completed one of two prior clinical studies (one Phase 2 and one Phase 3 [EPIDYS ...
Craig M. McDonald +74 more
wiley +1 more source
Diagnosis and management of cystinosis: systematic review for a clinical practice guideline
Background Cystinosis is a rare genetic disorder, with the majority of patients suffering from infantile nephropathic cystinosis, the most severe form. If left untreated, cystinosis causes serious morbidity, initially through progressive kidney and eye ...
Dominic Ledinger +7 more
doaj +1 more source
TECHNICAL EQUIPMENT AS A DIRECTION OF DEVELOPMENT OF PUBLIC ADMINISTRATION AT THE MODERN STAGE
In the article summarizes the transformations that affect public administration due to the equipment of spheres, environments, spaces and structures with technical means, which are characterized by wide volumes of functional capacity.
Oleh Bilyk, Olena Zharovska
doaj +1 more source
Durability of Response to B‐Cell Maturation Antigen‐Directed mRNA Cell Therapy in Myasthenia Gravis
ABSTRACT Objective We report the 12‐month follow‐up outcomes from a Phase 2 clinical trial (NCT04146051) evaluating Descartes‐08, a BCMA‐directed RNA chimeric antigen receptor T‐cell (rCAR‐T) therapy for refractory generalized myasthenia gravis (MG).
Nizar Chahin +10 more
wiley +1 more source
It has been shown that childhood trauma is associated with an increased risk of prodromal psychotic symptoms. However, research on the prevalence of prodromal psychotic symptoms among self-taught examination students and the relationship with childhood ...
Yanchi Wang +7 more
doaj +1 more source
人口老化趨勢及近年疫情大流行加速了中高齡數位學習之推動與普及,在此環境改變下,對高敏感特質的長輩是一大考驗。本研究旨在探討高敏感特質之中高齡者於疫情變化使數位學習環境更為普及之狀況下,所產生的數位學習壓力、心理憂鬱及學習滿意度的關聯,並以復原力作為中介變項,最後亦探討疫情趨緩後中高齡者在後疫情之感受。本研究採用問卷調查法進行資料蒐集,研究工具為高敏感特質、疫情焦慮、數位學習壓力、憂鬱情緒量表、學習滿意度、復原力及後疫情正向感受等7份量表;以45歲以上有數位學習經驗的中高齡者為研究對象 ...
王雅鈴 Ya-Ling Wang +3 more
doaj +1 more source

