Results 141 to 150 of about 8,254,986 (313)

TECHNICAL EQUIPMENT AS A DIRECTION OF DEVELOPMENT OF PUBLIC ADMINISTRATION AT THE MODERN STAGE

open access: yesПублічне управління та регіональний розвиток
In the article summarizes the transformations that affect public administration due to the equipment of spheres, environments, spaces and structures with technical means, which are characterized by wide volumes of functional capacity.
Oleh Bilyk, Olena Zharovska
doaj   +1 more source

The Development of a Self-Assessment Instrument to Evaluate Selected Competencies of Continuing Education Practitioners

open access: yes, 2005
Adult and continuing education practitioners must engage in continuing professional education as a means of developing and maintaining their professional competence.
Sullivan, Sherry
core   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

open access: yesFEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta   +7 more
wiley   +1 more source

Continuing Education Newsletter

open access: yes, 2019
Happy Holidays From The Division Of Continuing Education All About Birds The Division\u27s Mission GATA Self-Defense for Women Beekeeping ...
Continuing Education, Georgia Southern University
core  

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

open access: yesFEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen   +8 more
wiley   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

open access: yesFEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla   +10 more
wiley   +1 more source

Continuing Education for Women Newsletter, Vol. 1, No. 8

open access: yes, 1975
Source: University Archives Collection 1158, Information files,"Women's Continuing Education Program" 1970-79, Folder 2Continuing Education and Extension. (1975). Continuing Education for Women Newsletter, Vol. 1, No. 8.
Continuing Education and Extension
core  

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Continuing Education for Women, 1960-1975 Women's Day Program

open access: yes, 1975
Source: University Archives Collection 1158, Information files,"Women's Continuing Education Program" 1970-79, Folder 2Continuing Education for Women. (1975). Continuing Education for Women, 1960-1975 Women's Day Program.
Continuing Education for Women
core  

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