Results 81 to 90 of about 9,016,160 (399)

The context, influences and challenges for undergraduate nurse clinical education: Continuing the dialogue [PDF]

open access: yes, 2015
Introduction – Approaches to clinical education are highly diverse and becoming increasingly complex to sustain in complex milieu Objective – To identify the influences and challenges of providing nurse clinical education in the undergraduate setting ...
AIHW   +66 more
core   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Understanding Quantitative Circadian Regulations Are Crucial Towards Advancing Chronotherapy

open access: yesCells, 2019
Circadian rhythms have a deep impact on most aspects of physiology. In most organisms, especially mammals, the biological rhythms are maintained by the indigenous circadian clockwork around geophysical time (~24-h).
Debajyoti Chowdhury   +3 more
doaj   +1 more source

Revitalizing OCE [PDF]

open access: yes, 2015
Over the past two years, Linfield’s Online and Continuing Education program has undergone a transformation to revitalize offerings to appeal to a broader and changing ...
Mileham, Mardi
core   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

The Benefit of Continuing Professional Development for Continuing Pharmacy Education

open access: yesAmerican Journal of Pharmaceutical Education, 2017
As the health care environment undergoes rapid transformation, increasing costs paired with technological advancements have highlighted the need for value-based health care services and innovative models of delivery.
James S. Wheeler, M. Chisholm-Burns
semanticscholar   +1 more source

Medical Information Literacy and the Quality of the Medical Services. [PDF]

open access: yes, 2007
Information Literacy is the library operation which makes the library user able to search, retrieve, evaluate, select and use the information resources.
Katsirikou, Anthi
core  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

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