Results 101 to 110 of about 2,838,541 (319)
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Doubly stochastic continuous time random walk
Physical Review ResearchSince its introduction some 60 years ago, the Montroll-Weiss continuous time random walk has found numerous applications due its ease of use and ability to describe both regular and anomalous diffusion. Yet, despite its broad applicability and generality,
Maxence Arutkin, Shlomi Reuveni
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Stability of Continuous Time Difference Systems
Abstract and Applied AnalysisWe propose new sufficient conditions for the exponential stability of a class of nonlinear delay difference equations with continuous time (DECT). The above conditions provide a direct estimation of the exponential decay rate of the system.
Rigoberto Medina
doaj +1 more source
On the Continuous-Time Complementarity Problem
Trends in Computational and Applied MathematicsThis work deals with solving continuous-time nonlinear complementarity problems defined on two types of nonempty closed convex cones: a polyhedral cone (positive octant) and a second-order cone.
M. R. C. do Monte, V. A. de Oliveira
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
Five to 25 Gb/s continuous time linear equaliser with transversal architecture [PDF]
, 2017 H. Zhang +3 more
openalex +1 more source
Molecular Oncology, EarlyView.This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert +13 more
wiley +1 more source
Combat simulation using continuous time neural networks [PDF]
آیندهپژوهی دفاعی, 2018 This paper focuses on modeling the behavior of commanders in a combat simulation. A military mission is often associated with multiple conflicting goals, including task success, completion time, enemies’ elimination, and own forces survival.
Mohammad Moghaddas, Hamid Bigdeli
doaj