Results 31 to 40 of about 531,597 (256)

Widespread Myocardial Delivery of Heart-Derived Stem Cells by Nonocclusive Triple-Vessel Intracoronary Infusion in Porcine Ischemic Cardiomyopathy: Superior Attenuation of Adverse Remodeling Documented by Magnetic Resonance Imaging and Histology. [PDF]

PLoS ONE, 2016
Single-vessel, intracoronary infusion of stem cells under stop-flow conditions has proven safe but achieves only limited myocardial coverage. Continuous flow intracoronary delivery to one or more coronary vessels may achieve broader coverage for treating
Eleni Tseliou, Hideaki Kanazawa, James Dawkins, Romain Gallet, Michelle Kreke, Rachel Smith, Ryan Middleton, Jackelyn Valle, Linda Marbán, Saibal Kar, Rajendra Makkar, Eduardo Marbán   +11 more
doaj   +1 more source

Continuous Subcutaneous Levodopa Delivery for Parkinson’s Disease: A Randomized Study

Journal of Parkinson’s Disease, 2021
Background: ND0612 is a continuous, subcutaneous levodopa/carbidopa delivery system in development for patients with Parkinson’s disease (PD) experiencing motor fluctuations Objective: Evaluate the efficacy and safety of two ND0612 dosing regimens in ...
C. Warren Olanow, Alberto J. Espay, Fabrizio Stocchi, Aaron L. Ellenbogen, Mika Leinonen, Liat Adar, Ryan J. Case, Shir Fuchs Orenbach, Tami Yardeni, Sheila Oren, Werner Poewe,   +11 more
doaj   +1 more source

Continuous Drug Delivery Aiming Continuous Dopaminergic Stimulation in Parkinson’s Disease

Journal of Parkinson’s Disease, 2018
Continuous dopaminergic stimulation in Parkinson’s disease (PD) has several advantages over pulsatile, non-continuous, stimulation. These therapies currently consist of pump-based and transcutaneous therapies and are based on a more constant delivery of ...
Daniel J. van Wamelen, Sotirios Grigoriou, K. Ray Chaudhuri, Per Odin   +3 more
doaj   +1 more source

A machine learning approach to predict DevOps readiness and adaptation in a heterogeneous IT environment

Frontiers in Computer Science, 2023
Software and information systems have become a core competency for every business in this connected world. Any enhancement in software delivery and operations will tremendously impact businesses and society. Sustainable software development is one of the
Gopalakrishnan Sriraman, Shriram R.
doaj   +1 more source

The Port Delivery System with ranibizumab: a new paradigm for long-acting retinal drug delivery

Drug Delivery, 2022
The Port Delivery System with ranibizumab (PDS) is an innovative intraocular drug delivery system designed for the continuous delivery of ranibizumab into the vitreous for 6 months and beyond.
Shrirang V. Ranade, Mark R. Wieland, Tammy Tam, Jennifer C. Rea, Judit Horvath, Aaron R. Hieb, Weitao Jia, Lori Grace, Giulio Barteselli, Jay M. Stewart   +9 more
doaj   +1 more source

Carbon-Aware AI Control Plane for DevOps Automation: A Reference Architecture and Next-Generation Sustainability Framework

IEEE Access
This paper presents a reference architecture and conceptual framework for integrating carbon awareness into DevOps automation systems. AI workloads are becoming one of the fastest-growing contributors to the global computing demand; however, DevOps ...
Rohit Dhawan, Minav Suresh Patel
doaj   +1 more source

DEVELOPMENT OF A SOFTWARE CONTROLLER FOR THE AUTOMATED CREATION AND MANAGEMENT OF VIRTUAL RESOURCES FOR RUNNERS

Електроніка та інформаційні технології
The work developed a functional model (prototype) of the controller for the automated creation and management of runners’ virtual computing resources. The analysis of potential technologies for its implementation determined the choice of a combination of
Yu. Korchak, B. Mikh, Yuriy Furgala
doaj   +1 more source

Companionship during facility-based childbirth: results from a mixed-methods study with recently delivered women and providers in Kenya

BMC Pregnancy and Childbirth, 2018
Background Research suggests that birth companionship, and in particular, continuous support during labor and delivery, can improve women’s childbirth experience and birth outcomes.
Patience Afulani, Caroline Kusi, Leah Kirumbi, Dilys Walker   +3 more
doaj   +1 more source

Why do ‘OFF’ periods still occur during continuous drug delivery in Parkinson’s disease?

Translational Neurodegeneration, 2022
Continuous drug delivery (CDD) is used in moderately advanced and late-stage Parkinson’s disease (PD) to control motor and non-motor fluctuations (‘OFF’ periods).
Silvia Rota, Daniele Urso, Daniel J. van Wamelen, Valentina Leta, Iro Boura, Per Odin, Alberto J. Espay, Peter Jenner, K. Ray Chaudhuri   +8 more
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke, Christian Thomas, Michael C. Frühwald, Pascal D. Johann, Martin Hasselblatt   +4 more
wiley   +1 more source