Results 51 to 60 of about 133,395,779 (294)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Lipschitz continuous dependence of piecewise constant Lamé coefficients from boundary data: the case of non-flat interfaces [PDF]
Inverse Problems, 2014 We consider the inverse problem of determining the Lamé moduli for a piecewise constant elasticity tensor ${\mathbb C}= \sum_{j} {\mathbb C}_j χ_{D_j}$, where $\{D_j\}$ is a known finite partition of the body $Ω$, from the Dirichlet-to-Neumann map. We prove that Lipschitz stability estimates can be derived under $C^{1,α}$ regularity assumptions on the ...
Elena Beretta +4 more
openaire +3 more sources
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Инженерные технологии и системы, 2021 Introduction. To keep automobiles and tractors in operation conditions, it is necessary to restore the inner cylindrical surfaces of the friction pair parts. This is the most laborintensive activity.
Sergey Yu. Zhachkin +4 more
doaj +1 more source
Yet another proof that the roots of a polynomial depend continuously on the coefficients
, 2022 6 pages.
openaire +2 more sources
Continuous dependence on the Soret coefficient for double diffusive convection in Darcy flow
Journal of Mathematical Analysis and Applications, 2008 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Lin, Changhao, Payne, L.E.
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Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Continuous dependence for the Brinkman equations of flow in double-diffusive convection
Electronic Journal of Differential Equations, 2007 This paper concerns the structural stability for convective motion in a fluid-saturated porous medium under the Brinkman scheme. Continuous dependence for the solutions on the gravity coefficients and the Soret coefficient are proved. First of all,
Changhao Lin, Hongliang Tu
doaj
D-plots: Visualizations for Analysis of Bivariate Dependence Between Continuous Random Variables
StatsScatter plots are widely recognized as fundamental tools for illustrating the relationship between two numerical variables. Despite this, based on solid theoretical foundations, scatter plots generated from pairs of continuous random variables may not ...
Arturo Erdely, Manuel Rubio-Sánchez
doaj +1 more source