Results 71 to 80 of about 133,395,779 (294)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Thermal dependence of the strain response of optical fibre Bragg gratings. [PDF]

, 2004
The temperature dependence of the strain sensitivity of fibre Bragg gratings written into a number of different fibre types has been investigated. It was found that the strain response changed on average by 0.21 ± 0.03 fm µε-1 °C-1 over a range of ...
O'Dwyer, Martin, Ye, C. C., Ye, Chen-Chun, James, S. W., Tatam, Ralph P., O'Dwyer, M. J., Tatam, R. P., James, Stephen W., 叶陈春   +8 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Research and processing of ECG signals using discrete and continuous wavelet analysis

Sistemnì Doslìdženâ ta Informacìjnì Tehnologìï
The publication is devoted to analyzing electrocardiogram signals of artificial origin of realistic form with the possibility of controlling the duration, sampling frequency, noise level and pulse rate using Ingrid Daubechies wavelets.
Yurii Taranenko, Olha Oliynyk, Borys Moroz, Dmytro Moroz, Valerii Lopatin   +4 more
doaj   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

THE DYNAMICS OF TEMPERATURES CHANGING OF ROUND INGOT IN THE FIELD OF CUT AT ITS DRAWING ON THE MACHINE OF CONTINUOUS CASTING OF THE SMALL RADIUS SLUGS

Литьë и металлургия, 2006
The temperatures of the round ingot, produced in the machine of continuous casting with bending radius 5 meters, are calculated by means of numerical calculation.
A. N. Chichko, V. A. Matochkin, D. M. Kukuj, M. A. Murikov, A. V. Demin, O. I. Chichko   +5 more
doaj  

Free harmonic vibrations of an infinite string with periodic elastic supports [PDF]

AIP Advances
Free harmonic vibrations of an infinite string with a periodic system of elastic supports are investigated. The problem is formulated as a periodic multipoint spectral problem for the classical string vibration equation defined on the entire real axis ...
Alexandr A. Barsuk, Florentin Paladi
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Continuous or Batch Solid-Liquid Extraction of Antioxidant Compounds from Seeds of Sterculia apetala Plant and Kinetic Release Study

Molecules, 2018
This work has been intended to investigate the antioxidant properties of compounds extracted from seeds of Sterculia apetala (a plant from Central America) in order to add further results to the relatively poor existing literature on the beneficial ...
Federica Mosca, Gádor Indra Hidalgo, Juliana Villasante, María Pilar Almajano   +3 more
doaj   +1 more source

Dependence of axial propagation modes on piezoelectric coupling coefficients in a piezoelectric continuously twisted structurally chiral medium (PCTSCM) [PDF]

The Journal of the Acoustical Society of America, 1994
The material properties of a piezoelectric continuously twisted structurally chiral medium (PCTSCM) vary helicoidally along the axial direction. Monochromatic axial wave propagation in a PCTSCM has been solved exactly [A. Lakhtakia, Appl. Acoust. (in press)].
Steven F. Nagle, Akhlesh Lakhtakia
openaire   +1 more source