Results 61 to 70 of about 75,899 (254)

Research and processing of ECG signals using discrete and continuous wavelet analysis

Sistemnì Doslìdženâ ta Informacìjnì Tehnologìï
The publication is devoted to analyzing electrocardiogram signals of artificial origin of realistic form with the possibility of controlling the duration, sampling frequency, noise level and pulse rate using Ingrid Daubechies wavelets.
Yurii Taranenko, Olha Oliynyk, Borys Moroz, Dmytro Moroz, Valerii Lopatin   +4 more
doaj   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

THE DYNAMICS OF TEMPERATURES CHANGING OF ROUND INGOT IN THE FIELD OF CUT AT ITS DRAWING ON THE MACHINE OF CONTINUOUS CASTING OF THE SMALL RADIUS SLUGS

Литьë и металлургия, 2006
The temperatures of the round ingot, produced in the machine of continuous casting with bending radius 5 meters, are calculated by means of numerical calculation.
A. N. Chichko, V. A. Matochkin, D. M. Kukuj, M. A. Murikov, A. V. Demin, O. I. Chichko   +5 more
doaj  

Free harmonic vibrations of an infinite string with periodic elastic supports [PDF]

AIP Advances
Free harmonic vibrations of an infinite string with a periodic system of elastic supports are investigated. The problem is formulated as a periodic multipoint spectral problem for the classical string vibration equation defined on the entire real axis ...
Alexandr A. Barsuk, Florentin Paladi
doaj   +1 more source

Dependence of axial propagation modes on piezoelectric coupling coefficients in a piezoelectric continuously twisted structurally chiral medium (PCTSCM) [PDF]

The Journal of the Acoustical Society of America, 1994
The material properties of a piezoelectric continuously twisted structurally chiral medium (PCTSCM) vary helicoidally along the axial direction. Monochromatic axial wave propagation in a PCTSCM has been solved exactly [A. Lakhtakia, Appl. Acoust. (in press)].
Steven F. Nagle, Akhlesh Lakhtakia
openaire   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Continuous or Batch Solid-Liquid Extraction of Antioxidant Compounds from Seeds of Sterculia apetala Plant and Kinetic Release Study

Molecules, 2018
This work has been intended to investigate the antioxidant properties of compounds extracted from seeds of Sterculia apetala (a plant from Central America) in order to add further results to the relatively poor existing literature on the beneficial ...
Federica Mosca, Gádor Indra Hidalgo, Juliana Villasante, María Pilar Almajano   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Prediction of Time-Dependent Chloride Diffusion Coefficients for Slag-Blended Concrete

Advances in Materials Science and Engineering, 2017
The chloride diffusion coefficient is considered to be a key factor for evaluating the service life of ground-granulated blast-furnace slag (GGBS) blended concrete.
Ki-Bong Park, Han-Seung Lee, Xiao-Yong Wang   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source