Results 211 to 220 of about 572,064 (244)
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International Journal of Pharmaceutics, 2022
The pharmaceutical industry is continuously overcoming ways to reduce its development times to market and bring new medicines to patients with the highest quality standards faster.
M. Moreno-Benito +5 more
exaly +2 more sources
The pharmaceutical industry is continuously overcoming ways to reduce its development times to market and bring new medicines to patients with the highest quality standards faster.
M. Moreno-Benito +5 more
exaly +2 more sources
Starch Products as Candidate Excipients in a Continuous Direct Compression Line
Journal of Pharmaceutical Innovation, 2021Direct compression (DC) remains the most preferred technique to produce tablets, and its effectiveness is directly influenced by raw material attributes. Therefore, the selection of specific grades of excipients to achieve desirable powder flow and compression properties is of importance.
Sonia M. Razavi +7 more
semanticscholar +3 more sources
Continuous manufacturing of extended release tablets via powder mixing and direct compression
International Journal of Pharmaceutics, 2015The aim of the current work was to explore continuous dry powder mixing and direct compression for manufacturing of extended release (ER) matrix tablets. The study was span out with a challenging formulation design comprising ibuprofen compositions with varying particle size and a relatively low amount of the matrix former hydroxypropyl methylcellulose
Tuomas Ervasti +2 more
exaly +3 more sources
Chemical Engineering Research and Design, 2020
Continuous manufacturing of oral-dosage pharmaceuticals is widely understood to ensure consistent product quality and higher productivity at lower costs.
Shaun Galbraith +2 more
exaly +2 more sources
Continuous manufacturing of oral-dosage pharmaceuticals is widely understood to ensure consistent product quality and higher productivity at lower costs.
Shaun Galbraith +2 more
exaly +2 more sources
Pharmaceutical Development and Technology, 2018
Continuous manufacturing techniques are increasingly being adopted in the pharmaceutical industry and powder blending is a key operation for solid-dosage tablets. A modeling methodology involving axial and radial tanks-in-series flowsheet models is developed to describe the residence time distribution (RTD) and blend uniformity of a commercial powder ...
Shaun C, Galbraith +5 more
openaire +3 more sources
Continuous manufacturing techniques are increasingly being adopted in the pharmaceutical industry and powder blending is a key operation for solid-dosage tablets. A modeling methodology involving axial and radial tanks-in-series flowsheet models is developed to describe the residence time distribution (RTD) and blend uniformity of a commercial powder ...
Shaun C, Galbraith +5 more
openaire +3 more sources
Data-driven Modeling of a Continuous Direct Compression Tableting Process using SINDy
Systems and Control TransactionsUnderstanding the complex dynamics of continuous processes in pharmaceutical manufacturing is essential to ensure product quality across the production line. This paper presents a data-driven modeling approach using Sparse Identification of Nonlinear Dynamics with Control (SINDYc) to capture the dynamics of a continuous direct compression (CDC ...
Pau Lapiedra Carrasquer +4 more
openaire +2 more sources
Powder Technology, 2019
A flowsheet model for a continuous direct compression tableting process is developed and applied to process data generated at production scale. The model contains powder feeding, blending and tablet compaction unit operations. The dataset was provided by
Seongkyu Yoon
exaly +2 more sources
A flowsheet model for a continuous direct compression tableting process is developed and applied to process data generated at production scale. The model contains powder feeding, blending and tablet compaction unit operations. The dataset was provided by
Seongkyu Yoon
exaly +2 more sources
International Journal of Pharmaceutics, 2022
The ongoing transition from batch to continuous manufacturing offers both challenges and opportunities in the field of oral solid dosage form production. In turn, Process Analytical Technology (PAT) offers a path towards the successful deployment of continuous tablet manufacturing in rotary tablet presses.
Juan Pablo, Gallo-Molina +4 more
openaire +3 more sources
The ongoing transition from batch to continuous manufacturing offers both challenges and opportunities in the field of oral solid dosage form production. In turn, Process Analytical Technology (PAT) offers a path towards the successful deployment of continuous tablet manufacturing in rotary tablet presses.
Juan Pablo, Gallo-Molina +4 more
openaire +3 more sources
Pharmaceutical Development and Technology, 2020
Continuous manufacturing of oral-dosage drug products is increasing the need for rigorous process understanding both from a process design and control perspective.
Zhuangrong Huang +2 more
exaly +2 more sources
Continuous manufacturing of oral-dosage drug products is increasing the need for rigorous process understanding both from a process design and control perspective.
Zhuangrong Huang +2 more
exaly +2 more sources
Journal of Pharmaceutical Sciences, 2018
Continuous manufacturing of tablets has many advantages, including batch size flexibility, demand-adaptive scale up or scale down, consistent product quality, small operational foot print, and increased manufacturing efficiency. Simplicity makes direct compression the most suitable process for continuous tablet manufacturing.
Sayantan Chattoraj +1 more
exaly +3 more sources
Continuous manufacturing of tablets has many advantages, including batch size flexibility, demand-adaptive scale up or scale down, consistent product quality, small operational foot print, and increased manufacturing efficiency. Simplicity makes direct compression the most suitable process for continuous tablet manufacturing.
Sayantan Chattoraj +1 more
exaly +3 more sources