Results 51 to 60 of about 360,304 (270)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Effect of Al–5Ti–1B Addition on Solidification Microstructure and Hot Deformation Behavior of DC-Cast Al–Zn–Mg–Cu Alloy [PDF]

open access: yesArchives of Metallurgy and Materials
This study investigated the effect of adding Al–5Ti–1B grain refiner on the solidification microstructure and hot deformation behavior of direct-chill (DC) cast Al–Zn–Mg–Cu alloys. The grain refiner significantly decreased the grain size and modified the
Junho Lee   +7 more
doaj   +1 more source

Generalized bioinspired approach to a daytime radiative cooling "skin"

open access: yes, 2020
Energy-saving cooling materials with strong operability are desirable towards sustainable thermal management. Inspired by the cooperative thermo-optical effect in fur of polar bear, we develop a flexible and reusable cooling skin via laminating a ...
Guo, Jing   +9 more
core   +1 more source

Post-traumatic osteoarthritis in mice following mechanical injury to the synovial joint [PDF]

open access: yes, 2017
We investigated the spectrum of lesions characteristic of post-traumatic osteoarthritis (PTOA) across the knee joint in response to mechanical injury.
Chinzei, Nobuaki   +7 more
core   +3 more sources

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

Solving the Jitter Problem in Microwave Compressed Ultrafast Electron Diffraction Instruments: Robust Sub-50 fs Cavity-Laser Phase Stabilization

open access: yes, 2017
We demonstrate the compression of electron pulses in a high-brightness ultrafast electron diffraction (UED) instrument using phase-locked microwave signals directly generated from a mode-locked femtosecond oscillator.
de Cotret, Laurent P. Rene   +3 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Intra-firm Wage Compression and Cost Coverage of Training: Evidence from Linked Employer-Employee Data [PDF]

open access: yes, 2013
This paper uses German linked employer-employee data in order to estimate the impact of intra-firm wage dispersion on the probability that firms pay for continuous training.
Pfeifer, Christian
core  

Assessment of Tribo-charging and Continuous Feeding Performance of Direct Compression Grades of Isomalt and Mannitol Powders

open access: yesAAPS PharmSciTech, 2023
Abstract Tribo-charging is often a root cause of mass flow deviations and powder adhesion during continuous feeding. Thus, it may critically impact product quality. In this study, we characterized the volumetric (split- and pre-blend) feeding behavior and process-induced charge of two direct compression grades of polyols, galenIQ™ 721 (G721) for ...
Michela Beretta   +9 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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